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The Role of Epiretinal Membrane on Treatment of Neovascular Age-Related Macular Degeneration with Intravitreal Bevacizumab
Joint Authors
Ozkaya, Abdullah
Demirok, Ahmet
Karakucuk, Yalcin
Alkin, Zeynep
Yazici, Ahmet Taylan
Osmanbasoglu, Ozen Ayrancı
Agca, Alper
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Purpose.
To determine the effect of epiretinal membranes (ERM) on the treatment response and the number of intravitreal bevacizumab injections (IVB) in patients with neovascular age-related macular degeneration (nAMD).
Methods.
A retrospective chart review was performed on 63 eyes of 63 patients.
The patients were divided into AMD group (n=35) and AMD/ERM group (n=28).
Best corrected visual acuity (BCVA) and central retinal thickness (CRT), as well as the number of injections, were evaluated.
Results.
There was a significant improvement in BCVA at 3 months for the AMD and AMD/ERM groups (P=0.02, P=0.03, resp.).
At 6, 12, and 18 months, BCVA did not change significantly in either of the groups compared to baseline (P>0.05 for all).
At 3, 6, 12, and 24 months, the AMD group had an improvement in BCVA (logMAR) of 0.09, 0.06, 0.06, and 0.03 versus 0.08, 0.07, 0.05, and 0.03 for the AMD/ERM group (P=0.29, P=0.88, P=0.74, P=0.85, resp.).
A significant decrease in CRT occurred in both groups for all time points (P<0.001 for all).
The change in CRT was not statistically different between the two groups at all time points (P>0.05 for all).
The mean number of injections over 24 months was 8.8 in the AMD group and 9.2 in the AMD/ERM group (P=0.76).
Conclusion.
During 24 months, visual and anatomical outcomes of IVB in nAMD patients were comparable with those in nAMD patients with ERM with similar injection numbers.
American Psychological Association (APA)
Alkin, Zeynep& Ozkaya, Abdullah& Osmanbasoglu, Ozen Ayrancı& Agca, Alper& Karakucuk, Yalcin& Yazici, Ahmet Taylan…[et al.]. 2013. The Role of Epiretinal Membrane on Treatment of Neovascular Age-Related Macular Degeneration with Intravitreal Bevacizumab. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1033492
Modern Language Association (MLA)
Alkin, Zeynep…[et al.]. The Role of Epiretinal Membrane on Treatment of Neovascular Age-Related Macular Degeneration with Intravitreal Bevacizumab. The Scientific World Journal No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1033492
American Medical Association (AMA)
Alkin, Zeynep& Ozkaya, Abdullah& Osmanbasoglu, Ozen Ayrancı& Agca, Alper& Karakucuk, Yalcin& Yazici, Ahmet Taylan…[et al.]. The Role of Epiretinal Membrane on Treatment of Neovascular Age-Related Macular Degeneration with Intravitreal Bevacizumab. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1033492
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1033492