Statistical Optimization of Process Parameters for Lipase-Catalyzed Synthesis of Triethanolamine-Based Esterquats Using Response Surface Methodology in 2-Liter Bioreactor
Joint Authors
Basri, Mahiran
Fard Masoumi, Hamid Reza
Kassim, Anuar
Kuang Abdullah, Dzulkefly
Abdollahi, Yadollah
Abd Gani, Siti Salwa
Rezaee, Malahat
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-10
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Lipase-catalyzed production of triethanolamine-based esterquat by esterification of oleic acid (OA) with triethanolamine (TEA) in n-hexane was performed in 2 L stirred-tank reactor.
A set of experiments was designed by central composite design to process modeling and statistically evaluate the findings.
Five independent process variables, including enzyme amount, reaction time, reaction temperature, substrates molar ratio of OA to TEA, and agitation speed, were studied under the given conditions designed by Design Expert software.
Experimental data were examined for normality test before data processing stage and skewness and kurtosis indices were determined.
The mathematical model developed was found to be adequate and statistically accurate to predict the optimum conversion of product.
Response surface methodology with central composite design gave the best performance in this study, and the methodology as a whole has been proven to be adequate for the design and optimization of the enzymatic process.
American Psychological Association (APA)
Fard Masoumi, Hamid Reza& Basri, Mahiran& Kassim, Anuar& Kuang Abdullah, Dzulkefly& Abdollahi, Yadollah& Abd Gani, Siti Salwa…[et al.]. 2013. Statistical Optimization of Process Parameters for Lipase-Catalyzed Synthesis of Triethanolamine-Based Esterquats Using Response Surface Methodology in 2-Liter Bioreactor. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1033494
Modern Language Association (MLA)
Fard Masoumi, Hamid Reza…[et al.]. Statistical Optimization of Process Parameters for Lipase-Catalyzed Synthesis of Triethanolamine-Based Esterquats Using Response Surface Methodology in 2-Liter Bioreactor. The Scientific World Journal No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1033494
American Medical Association (AMA)
Fard Masoumi, Hamid Reza& Basri, Mahiran& Kassim, Anuar& Kuang Abdullah, Dzulkefly& Abdollahi, Yadollah& Abd Gani, Siti Salwa…[et al.]. Statistical Optimization of Process Parameters for Lipase-Catalyzed Synthesis of Triethanolamine-Based Esterquats Using Response Surface Methodology in 2-Liter Bioreactor. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1033494
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1033494