Contribution of Crk Adaptor Proteins to Host Cell and Bacteria Interactions
Joint Authors
Feuerbacher, Leigh Ann
Benito-León, María
Hardwidge, Philip R.
Martinez-Quiles, N.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-24
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
The Crk adaptor family of proteins comprises the alternatively spliced CrkI and CrkII isoforms, as well as the paralog Crk-like (CrkL) protein, which is encoded by a different gene.
Initially thought to be involved in signaling during apoptosis and cell adhesion, this ubiquitously expressed family of proteins is now known to play essential roles in integrating signals from a wide range of stimuli.
In this review, we describe the structure and function of the different Crk proteins.
We then focus on the emerging roles of Crk adaptors during Enterobacteriaceae pathogenesis, with special emphasis on the important human pathogens Salmonella, Shigella, Yersinia, and enteropathogenic Escherichia coli.
Throughout, we remark on opportunities for future research into this intriguing family of proteins.
American Psychological Association (APA)
Martinez-Quiles, N.& Feuerbacher, Leigh Ann& Benito-León, María& Hardwidge, Philip R.. 2014. Contribution of Crk Adaptor Proteins to Host Cell and Bacteria Interactions. BioMed Research International،Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-1034445
Modern Language Association (MLA)
Martinez-Quiles, N.…[et al.]. Contribution of Crk Adaptor Proteins to Host Cell and Bacteria Interactions. BioMed Research International No. 2014 (2014), pp.1-13.
https://search.emarefa.net/detail/BIM-1034445
American Medical Association (AMA)
Martinez-Quiles, N.& Feuerbacher, Leigh Ann& Benito-León, María& Hardwidge, Philip R.. Contribution of Crk Adaptor Proteins to Host Cell and Bacteria Interactions. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-1034445
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034445