Tissue Engineered Scaffolds for an Effective Healing and Regeneration: Reviewing Orthotopic Studies
Joint Authors
Urbani, Luca
Baiguera, Silvia
Del Gaudio, Costantino
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-27, 27 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-27
Country of Publication
Egypt
No. of Pages
27
Main Subjects
Abstract EN
It is commonly stated that tissue engineering is the most promising approach to treat or replace failing tissues/organs.
For this aim, a specific strategy should be planned including proper selection of biomaterials, fabrication techniques, cell lines, and signaling cues.
A great effort has been pursued to develop suitable scaffolds for the restoration of a variety of tissues and a huge number of protocols ranging from in vitro to in vivo studies, the latter further differentiating into several procedures depending on the type of implantation (i.e., subcutaneous or orthotopic) and the model adopted (i.e., animal or human), have been developed.
All together, the published reports demonstrate that the proposed tissue engineering approaches spread toward multiple directions.
The critical review of this scenario might suggest, at the same time, that a limited number of studies gave a real improvement to the field, especially referring to in vivo investigations.
In this regard, the present paper aims to review the results of in vivo tissue engineering experimentations, focusing on the role of the scaffold and its specificity with respect to the tissue to be regenerated, in order to verify whether an extracellular matrix-like device, as usually stated, could promote an expected positive outcome.
American Psychological Association (APA)
Baiguera, Silvia& Urbani, Luca& Del Gaudio, Costantino. 2014. Tissue Engineered Scaffolds for an Effective Healing and Regeneration: Reviewing Orthotopic Studies. BioMed Research International،Vol. 2014, no. 2014, pp.1-27.
https://search.emarefa.net/detail/BIM-1034451
Modern Language Association (MLA)
Baiguera, Silvia…[et al.]. Tissue Engineered Scaffolds for an Effective Healing and Regeneration: Reviewing Orthotopic Studies. BioMed Research International No. 2014 (2014), pp.1-27.
https://search.emarefa.net/detail/BIM-1034451
American Medical Association (AMA)
Baiguera, Silvia& Urbani, Luca& Del Gaudio, Costantino. Tissue Engineered Scaffolds for an Effective Healing and Regeneration: Reviewing Orthotopic Studies. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-27.
https://search.emarefa.net/detail/BIM-1034451
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034451