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Levels of Soluble E-Cadherin in Breast, Gastric, and Colorectal Cancers
Joint Authors
Repetto, Ombretta
De Re, Valli
Cannizzaro, Renato
Canzonieri, Vincenzo
De Paoli, Paolo
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Soluble E-cadherin is a 80 kDa protein fragment coming from the proteolytic cleavage of the extracellular domain of the full length epithelial cadherin, a molecule involved in cell adhesion/polarity and tissue morphogenesis.
In comparison with normal epithelia, cancer cells show a decreased cadherin-mediated intercellular adhesion, and sE-cad levels normally increase in body fluids (blood and urine).
This review focuses on soluble E-cadherin in sera of patients affected by three solid cancers (breast, gastric, and colorectal cancers) and how its levels correlate or not with some cancer parameters (e.g., dimension, progression, and localisation).
We will describe the main proteomics approaches adopted to measure sE-cad both in vivo and in vitro and the most important findings about its behaviour in cancer dynamics.
American Psychological Association (APA)
Repetto, Ombretta& De Paoli, Paolo& De Re, Valli& Canzonieri, Vincenzo& Cannizzaro, Renato. 2014. Levels of Soluble E-Cadherin in Breast, Gastric, and Colorectal Cancers. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1034454
Modern Language Association (MLA)
Repetto, Ombretta…[et al.]. Levels of Soluble E-Cadherin in Breast, Gastric, and Colorectal Cancers. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1034454
American Medical Association (AMA)
Repetto, Ombretta& De Paoli, Paolo& De Re, Valli& Canzonieri, Vincenzo& Cannizzaro, Renato. Levels of Soluble E-Cadherin in Breast, Gastric, and Colorectal Cancers. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1034454
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034454