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Heat Shock Protein 70 in Alzheimer’s Disease
Joint Authors
Lu, Rui-Chun
Xie, An-Mu
Tan, Lan
Tan, Meng-Shan
Yu, Jin-Tai
Wang, Hao
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-06
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Alzheimer’s disease (AD) is the most common neurodegenerative disease that caused dementia which has no effective treatment.
Growing evidence has demonstrated that AD is a “protein misfolding disorder” that exhibits common features of misfolded, aggregation-prone proteins and selective cell loss in the mature nervous system.
Heat shock protein 70 (HSP70) attracts extensive attention worldwide, because it plays a crucial role in preventing protein misfolding and inhibiting aggregation and represents a class of proteins potentially involved in AD pathogenesis.
Numerous studies have indicated that HSP70 could suppress the progression of AD with in vitro and in vivo experiments.
Thus, targeting HSP70 and the related compounds might represent a promising strategy for the treatment of AD.
American Psychological Association (APA)
Lu, Rui-Chun& Tan, Meng-Shan& Wang, Hao& Xie, An-Mu& Yu, Jin-Tai& Tan, Lan. 2014. Heat Shock Protein 70 in Alzheimer’s Disease. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1034464
Modern Language Association (MLA)
Lu, Rui-Chun…[et al.]. Heat Shock Protein 70 in Alzheimer’s Disease. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1034464
American Medical Association (AMA)
Lu, Rui-Chun& Tan, Meng-Shan& Wang, Hao& Xie, An-Mu& Yu, Jin-Tai& Tan, Lan. Heat Shock Protein 70 in Alzheimer’s Disease. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1034464
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034464