Clinical Evaluation of the Regenerative Potential of EMD and NanoHA in Periodontal Infrabony Defects: A 2-Year Follow-Up
Joint Authors
Pilloni, Andrea
Polimeni, Antonella
Saccucci, Matteo
Di Carlo, Gabriele
Zeza, Blerina
Ambrosca, Marco
Paolantonio, Michele
Mongardini, Claudio
Sammartino, Gilberto
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Introduction.
The aim of this retrospective study was to compare the clinical efficacy of four different surgical techniques in promoting periodontal regeneration in patients with infrabony defects: open flap debridement, application of enamel matrix derivatives (EMD), nanohydroxyapatite (nanoHA) application, and combined nanoHA and EMD application.
Probing attachment level (PAL), pocket depth (PD), and position of gingival margin at completion of therapy (REC) were measured.
Materials and Methods.
Data were collected from 64 healthy patients (34 women and 30 men, mean age 37,7 years).
Clinical indices were measured by a calibrated examiner at baseline and at 12, 18, and 24 months.
The values obtained for each treatment were compared using nonparametric tests.
Results.
All treatments resulted in a tendency toward PD reduction over time, with improvements in REC and PAL.
The differences in PD, REC, and PAL values at baseline compared with values after 12, 18, and 24 months were statistically significant for all treatments.
Statistically significant differences in PAL and PD were detected between nanoHA and nanoHA + EMD at 12, 18, and 24 months.
Conclusion.
In this study, EMD and nanoHA used together in patients with infrabony periodontal lesions had better clinical efficacy than nanoHA alone, EMD alone, or open flap debridement.
American Psychological Association (APA)
Pilloni, Andrea& Saccucci, Matteo& Di Carlo, Gabriele& Zeza, Blerina& Ambrosca, Marco& Paolantonio, Michele…[et al.]. 2014. Clinical Evaluation of the Regenerative Potential of EMD and NanoHA in Periodontal Infrabony Defects: A 2-Year Follow-Up. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1034478
Modern Language Association (MLA)
Pilloni, Andrea…[et al.]. Clinical Evaluation of the Regenerative Potential of EMD and NanoHA in Periodontal Infrabony Defects: A 2-Year Follow-Up. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1034478
American Medical Association (AMA)
Pilloni, Andrea& Saccucci, Matteo& Di Carlo, Gabriele& Zeza, Blerina& Ambrosca, Marco& Paolantonio, Michele…[et al.]. Clinical Evaluation of the Regenerative Potential of EMD and NanoHA in Periodontal Infrabony Defects: A 2-Year Follow-Up. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1034478
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034478