Changing Interdigestive Migrating Motor Complex in Rats under Acute Liver Injury
Joint Authors
Zhang, Jian-Ying
Liu, Mei
Zheng, Su-Jun
Xu, Weihong
Chen, Yu
Duan, Zhongping
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-10-28
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Gastrointestinal motility disorder is a major clinical manifestation of acute liver injury, and interdigestive migrating motor complex (MMC) is an important indicator.
We investigated the changes and characteristics of MMC in rats with acute liver injury.
Acute liver injury was created by d-galactosamine, and we recorded the interdigestive MMC using a multichannel physiological recorder and compared the indexes of interdigestive MMC.
Compared with normal controls, antral MMC Phase I duration was significantly prolonged and MMC Phase III duration was significantly shortened in the rats with acute liver injury.
The duodenal MMC cycle and MMC Phases I and IV duration were significantly prolonged and MMC Phase III duration was significantly shortened in the rats with acute liver injury.
The jejunal MMC cycle and MMC Phases I and IV duration were significantly prolonged and MMC Phase III duration was significantly shortened in the rats with acute liver injury compared with normal controls.
Compared with the normal controls, rats with acute liver injury had a significantly prolonged interdigestive MMC cycle, related mainly to longer MMC Phases I and IV, shortened MMC Phase III, and MMC Phase II characterized by increased migrating clustered contractions, which were probably major contributors to the gastrointestinal motility disorders.
American Psychological Association (APA)
Liu, Mei& Zheng, Su-Jun& Xu, Weihong& Zhang, Jian-Ying& Chen, Yu& Duan, Zhongping. 2014. Changing Interdigestive Migrating Motor Complex in Rats under Acute Liver Injury. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1034517
Modern Language Association (MLA)
Liu, Mei…[et al.]. Changing Interdigestive Migrating Motor Complex in Rats under Acute Liver Injury. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1034517
American Medical Association (AMA)
Liu, Mei& Zheng, Su-Jun& Xu, Weihong& Zhang, Jian-Ying& Chen, Yu& Duan, Zhongping. Changing Interdigestive Migrating Motor Complex in Rats under Acute Liver Injury. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1034517
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034517