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Impact of the Prolymphangiogenic Crosstalk in the Tumor Microenvironment on Lymphatic Cancer Metastasis
Joint Authors
Schlereth, Simona L.
Refaian, Nasrin
Iden, Sandra
Heindl, Ludwig M.
Cursiefen, Claus
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-01
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Lymphangiogenesis is a very early step in lymphatic metastasis.
It is regulated and promoted not only by the tumor cells themselves, but also by cells of the tumor microenvironment, including cancer associated fibroblasts, mesenchymal stem cells, dendritic cells, or macrophages.
Even the extracellular matrix as well as cytokines and growth factors are involved in the process of lymphangiogenesis and metastasis.
The cellular and noncellular components influence each other and can be influenced by the tumor cells.
The knowledge about mechanisms behind lymphangiogenesis in the tumor microenvironmental crosstalk is growing and offers starting points for new therapeutic approaches.
American Psychological Association (APA)
Schlereth, Simona L.& Refaian, Nasrin& Iden, Sandra& Cursiefen, Claus& Heindl, Ludwig M.. 2014. Impact of the Prolymphangiogenic Crosstalk in the Tumor Microenvironment on Lymphatic Cancer Metastasis. BioMed Research International،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-1034521
Modern Language Association (MLA)
Schlereth, Simona L.…[et al.]. Impact of the Prolymphangiogenic Crosstalk in the Tumor Microenvironment on Lymphatic Cancer Metastasis. BioMed Research International No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-1034521
American Medical Association (AMA)
Schlereth, Simona L.& Refaian, Nasrin& Iden, Sandra& Cursiefen, Claus& Heindl, Ludwig M.. Impact of the Prolymphangiogenic Crosstalk in the Tumor Microenvironment on Lymphatic Cancer Metastasis. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-1034521
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034521