Scotopic Microperimetry in the Early Diagnosis of Age-Related Macular Degeneration: Preliminary Study
Joint Authors
Barbato, Andrea
Pescosolido, Nicola
Nebbioso, Marcella
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Recent clinical studies have shown that, in some degenerative retinal diseases, like age-related macular degeneration (AMD), the sensitivity of the rods decreases more rapidly than the sensitivity of the cones.
The aim of this study was to evaluate if there is a correlation between the presence of hard drusen at the macular level and the rod damage responsible for the reduction in scotopic retinal sensitivity in subjects at risk for AMD.
Methods.
The authors selected 24 subjects (14 men and 10 women) with an average age of 67.25 ± 5.7 years.
Macular hard drusen were present in 50% of the subjects at the fundus oculi exam.
The researchers evaluated the retinal sensitivity to light in mesopic and scotopic conditions of each subject with an MP-1 scotopic microperimeter (MP-1S).
Results.
In subjects with hard drusen in the fundus oculi examination, there was a statistically significant reduction in scotopic retinal sensitivity, while the mesopic retinal sensitivity was not compromised.
Conclusion.
This study revealed how the presence of hard drusen at the macular level is associated with a reduction in scotopic retinal sensitivity compared to a control group of healthy subjects.
Retinal functionality in a scotopic setting examined with MP-1S could be useful in early diagnosis of AMD.
American Psychological Association (APA)
Nebbioso, Marcella& Barbato, Andrea& Pescosolido, Nicola. 2014. Scotopic Microperimetry in the Early Diagnosis of Age-Related Macular Degeneration: Preliminary Study. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1034529
Modern Language Association (MLA)
Nebbioso, Marcella…[et al.]. Scotopic Microperimetry in the Early Diagnosis of Age-Related Macular Degeneration: Preliminary Study. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1034529
American Medical Association (AMA)
Nebbioso, Marcella& Barbato, Andrea& Pescosolido, Nicola. Scotopic Microperimetry in the Early Diagnosis of Age-Related Macular Degeneration: Preliminary Study. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1034529
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034529