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Carbon Ion Therapy for Early-Stage Non-Small-Cell Lung Cancer
Joint Authors
Demizu, Yusuke
Fujii, Osamu
Iwata, Hiromitsu
Fuwa, Nobukazu
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-10
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Carbon ion therapy is a type of radiotherapies that can deliver high-dose radiation to a tumor while minimizing the dose delivered to the organs at risk; this profile differs from that of photon radiotherapy.
Moreover, carbon ions are classified as high-linear energy transfer radiation and are expected to be effective for even photon-resistant tumors.
Recently, high-precision radiotherapy modalities such as stereotactic body radiotherapy (SBRT), proton therapy, and carbon ion therapy have been used for patients with early-stage non-small-cell lung cancer, and the results are promising, as, for carbon ion therapy, local control and overall survival rates at 5 years are 80–90% and 40–50%, respectively.
Carbon ion therapy may be theoretically superior to SBRT and proton therapy, but the literature that is currently available does not show a statistically significant difference among these treatments.
Carbon ion therapy demonstrates a better dose distribution than both SBRT and proton therapy in most cases of early-stage lung cancer.
Therefore, carbon ion therapy may be safer for treating patients with adverse conditions such as large tumors, central tumors, and poor pulmonary function.
Furthermore, carbon ion therapy may also be suitable for dose escalation and hypofractionation.
American Psychological Association (APA)
Demizu, Yusuke& Fujii, Osamu& Iwata, Hiromitsu& Fuwa, Nobukazu. 2014. Carbon Ion Therapy for Early-Stage Non-Small-Cell Lung Cancer. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1034550
Modern Language Association (MLA)
Demizu, Yusuke…[et al.]. Carbon Ion Therapy for Early-Stage Non-Small-Cell Lung Cancer. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1034550
American Medical Association (AMA)
Demizu, Yusuke& Fujii, Osamu& Iwata, Hiromitsu& Fuwa, Nobukazu. Carbon Ion Therapy for Early-Stage Non-Small-Cell Lung Cancer. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1034550
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034550