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A Novel Approach for Development and Characterization of Effective Mosquito Repellent Cream Formulation Containing Citronella Oil
Joint Authors
Yadav, Narayan Prasad
Sinha, Priyam
Chanotiya, C. S.
Rai, Vineet Kumar
Bawankule, Dnyaneshwar Umrao
Pal, Anirban
Tripathi, Arun Kumar
Mishra, Nidhi
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-10-14
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Citronella essential oil (CEO) has been reported as an excellent mosquito repellent; however, mild irritancy and rapid volatility limit its topical application.
It was aimed to develop a nonirritant, stable, and consistent cream of CEO with improved residence time on skin using an industrial approach.
Phase inversion temperature technique was employed to prepare the cream.
It was optimized and characterized based on sensorial evaluation, emulsification, and consistency in terms of softness, greasiness, stickiness, and pH.
The optimum batch (B5) was evaluated for viscosity (90249.67 ± 139.95 cP), texture profile with respect to firmness (38.67 ± 0.88 g), spreadability (70.33 ± 0.88 mJ), and extrudability (639.67 ± 8.09 ± 0.1 mJ) using texture analyzer along with two most popular marketed products selected as reference standard.
Subsequently, B5 was found to be stable for more than 90 days and showed enhanced duration of mosquito repellency as compared to CEO.
HS-GC ensured the intactness of CEO in B5.
Investigated primary irritation index (PII 0.45) positioned B5 into the category of irritation barely perceptible.
The pronounced texture profile and stability of B5 with extended residence time and less PII revealed its potential application in industry and offered a promising alternative to the marketed products of synthetic origin.
American Psychological Association (APA)
Yadav, Narayan Prasad& Rai, Vineet Kumar& Mishra, Nidhi& Sinha, Priyam& Bawankule, Dnyaneshwar Umrao& Pal, Anirban…[et al.]. 2014. A Novel Approach for Development and Characterization of Effective Mosquito Repellent Cream Formulation Containing Citronella Oil. BioMed Research International،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1034564
Modern Language Association (MLA)
Yadav, Narayan Prasad…[et al.]. A Novel Approach for Development and Characterization of Effective Mosquito Repellent Cream Formulation Containing Citronella Oil. BioMed Research International No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1034564
American Medical Association (AMA)
Yadav, Narayan Prasad& Rai, Vineet Kumar& Mishra, Nidhi& Sinha, Priyam& Bawankule, Dnyaneshwar Umrao& Pal, Anirban…[et al.]. A Novel Approach for Development and Characterization of Effective Mosquito Repellent Cream Formulation Containing Citronella Oil. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1034564
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034564