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Serum Metal Ion Concentrations in Paediatric Patients following Total Knee Arthroplasty Using Megaprostheses
Joint Authors
Leithner, Andreas
Sadoghi, Patrick
Szkandera, Joanna
Glehr, Mathias
Ogris, Kathrin
Wolf, Matthias
Weger, Christian
Friesenbichler, Joerg
Maurer-Ertl, Werner
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The purpose of this study was to determine the concentrations of cobalt, chromium, and molybdenum in the serum of paediatric tumour patients after fixed hinge total knee arthroplasty.
Further, these metal ion levels were compared with serum metal ion levels of patients with other orthopaedic devices such as hip and knee prostheses with metal-on-metal or metal-on-polyethylene articulation to find differences between anatomical locations, abrasion characteristics, and bearing surfaces.
After an average follow-up of 108 months (range: 67 to 163) of 11 paediatric patients with fixed hinge total knee arthroplasty, the mean concentrations for Co and Cr were significantly increased while Mo was within the limits compared to the upper values from the reference laboratory.
Furthermore, these serum concentrations were significantly higher compared to patients with a standard rotating hinge device ( P = 0.002 and P < 0.001 ) and preoperative controls ( P < 0.001 ) .
On the other hand, the serum levels of patients following MoM THA or rotating hinge arthroplasty using megaprostheses were higher.
Therefore, periodic long-term follow-ups are recommended due to the rising concerns about systemic metal ion exposure in the literature.
Upon the occurrence of adverse reactions to metal debris the revision of the fixed hinge implant should be considered.
American Psychological Association (APA)
Friesenbichler, Joerg& Sadoghi, Patrick& Maurer-Ertl, Werner& Szkandera, Joanna& Glehr, Mathias& Ogris, Kathrin…[et al.]. 2014. Serum Metal Ion Concentrations in Paediatric Patients following Total Knee Arthroplasty Using Megaprostheses. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1034575
Modern Language Association (MLA)
Friesenbichler, Joerg…[et al.]. Serum Metal Ion Concentrations in Paediatric Patients following Total Knee Arthroplasty Using Megaprostheses. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1034575
American Medical Association (AMA)
Friesenbichler, Joerg& Sadoghi, Patrick& Maurer-Ertl, Werner& Szkandera, Joanna& Glehr, Mathias& Ogris, Kathrin…[et al.]. Serum Metal Ion Concentrations in Paediatric Patients following Total Knee Arthroplasty Using Megaprostheses. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1034575
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034575