Serial Changes of Neointimal Tissue after Everolimus-Eluting Stent Implantation in Porcine Coronary Artery: An Optical Coherence Tomography Analysis
Joint Authors
Won, Hoyoun
Kim, Jung-Sun
Shin, Dong-Ho
Kim, Byeong-Keuk
Ko, Young-Guk
Jang, Yangsoo
Hong, Myeong-Ki
Choi, Dong Hoon
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-17
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purposes.
The serial changes in neointimal tissues were compared between everolimus-eluting stent (EES) and bare-metal stent (BMS) in the porcine coronary artery using optical coherence tomography (OCT).
Methods.
Serial (1, 3, and 6 month follow-up after stent implantation) OCT examinations were performed in 15 swine with 15 BMS- and 15 EES-treated lesions in porcine coronary arteries.
Results.
In BMS-implanted lesions, neointimal volume decreased from 7.3 mm3 to 6.9 mm3 and 6.4 mm3 at 1, 3, and 6 months follow-up without statistical significance (P=0.369).
At the time points of 1, 3, and 6 months, neointimal tissue appearance was mainly a homogeneous pattern (80.0%, 93.3%, and 100%, resp.), while the other pattern was layered.
In contrast, in EES-implanted lesions, neointimal volume significantly increased from 4.8 mm3 to 9.8 mm3 between 1 and 3 months but significantly decreased to 8.6 mm3 between 3 and 6 months (P<0.001).
Between 1 and 3 months, the layered pattern of neointimal tissue increased from 26.7% to 66.7% but decreased to 20.0% between 3 and 6 months.
Conclusions.
EES had a biphasic pattern of neointimal amounts that correlated with changes in neointimal morphology.
American Psychological Association (APA)
Won, Hoyoun& Kim, Jung-Sun& Shin, Dong-Ho& Kim, Byeong-Keuk& Ko, Young-Guk& Choi, Dong Hoon…[et al.]. 2014. Serial Changes of Neointimal Tissue after Everolimus-Eluting Stent Implantation in Porcine Coronary Artery: An Optical Coherence Tomography Analysis. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1034583
Modern Language Association (MLA)
Won, Hoyoun…[et al.]. Serial Changes of Neointimal Tissue after Everolimus-Eluting Stent Implantation in Porcine Coronary Artery: An Optical Coherence Tomography Analysis. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1034583
American Medical Association (AMA)
Won, Hoyoun& Kim, Jung-Sun& Shin, Dong-Ho& Kim, Byeong-Keuk& Ko, Young-Guk& Choi, Dong Hoon…[et al.]. Serial Changes of Neointimal Tissue after Everolimus-Eluting Stent Implantation in Porcine Coronary Artery: An Optical Coherence Tomography Analysis. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1034583
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034583