Prefronto-Cerebellar Transcranial Direct Current Stimulation Improves Sleep Quality in Euthymic Bipolar Patients: A Brief Report
Joint Authors
Minichino, Amedeo
Spagnoli, Francesco
Corrado, Alessandra
De Michele, Francesco
Calò, Wanda Katharina
Primavera, Martina
Yang, Baoran
Bernabei, Laura
Macrì, Francesco
Vergnani, Lucilla
Biondi, Massimo
Delle Chiaie, Roberto
Bersani, Francesco Saverio
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-04
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Introduction.
Sleep problems are common in bipolar disorder (BD) and may persist during the euthymic phase of the disease.
The aim of the study was to improve sleep quality of euthymic BD patients through the administration of prefronto-cerebellar transcranial direct current stimulation (tDCS).
Methods.
25 euthymic outpatients with a diagnosis of BD Type I or II have been enrolled in the study.
tDCS montage was as follows: cathode on the right cerebellar cortex and anode over the left dorsolateral prefrontal cortex (DLPFC); the intensity of stimulation was set at 2 mA and delivered for 20 min/die for 3 consecutive weeks.
The Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality at baseline and after the tDCS treatment.
Results.
PSQI total score and all PSQI subdomains, with the exception of “sleep medication,” significantly improved after treatment.
Discussion.
This is the first study where a positive effect of tDCS on the quality of sleep in euthymic BD patients has been reported.
As both prefrontal cortex and cerebellum may play a role in regulating sleep processes, concomitant cathodal (inhibitory) stimulation of cerebellum and anodal (excitatory) stimulation of DLPFC may have the potential to modulate prefrontal-thalamic-cerebellar circuits leading to improvements of sleep quality.
American Psychological Association (APA)
Minichino, Amedeo& Bersani, Francesco Saverio& Spagnoli, Francesco& Corrado, Alessandra& De Michele, Francesco& Calò, Wanda Katharina…[et al.]. 2014. Prefronto-Cerebellar Transcranial Direct Current Stimulation Improves Sleep Quality in Euthymic Bipolar Patients: A Brief Report. Behavioural Neurology،Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-1034625
Modern Language Association (MLA)
Minichino, Amedeo…[et al.]. Prefronto-Cerebellar Transcranial Direct Current Stimulation Improves Sleep Quality in Euthymic Bipolar Patients: A Brief Report. Behavioural Neurology No. 2014 (2014), pp.1-3.
https://search.emarefa.net/detail/BIM-1034625
American Medical Association (AMA)
Minichino, Amedeo& Bersani, Francesco Saverio& Spagnoli, Francesco& Corrado, Alessandra& De Michele, Francesco& Calò, Wanda Katharina…[et al.]. Prefronto-Cerebellar Transcranial Direct Current Stimulation Improves Sleep Quality in Euthymic Bipolar Patients: A Brief Report. Behavioural Neurology. 2014. Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-1034625
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034625