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Primary Squamous Cell Carcinoma of the Thyroid Diagnosed as Anaplastic Carcinoma: Failure in Fine-Needle Aspiration Cytology?
Joint Authors
Soares, Paula
Bolfi, Fernanda
Domingues, Maria A. C.
Sobrinho-Simões, Manuel
Celestino, Ricardo
Carelli, Guareide
Paes, Norberto S.
Mazeto, Glaucia Maria Ferreira da Silva
Castilho, Emanuel Cellice
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-09
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
A case of primary squamous-cell carcinoma (SCC) of the thyroid which had been initially diagnosed as an anaplastic carcinoma (ATC) is described: female, 73 years old, with a fast-growing cervical nodule on the left side and hoarseness for 3 months.
Ultrasonography showed a 4.5 cm solid nodule.
FNA was compatible with poorly differentiated carcinoma with immunoreactivity for AE1/AE3, EMA.
Thyroidectomy was performed.
Histopathological examination showed a nonencapsulated tumor.
Immunohistochemistry disclosed positivity for AE1/AE3, p53,p63, and Ki67.
The diagnosis was ATC.
A second opinion reported tumor consisting of squamous cells, with intense inflammatory infiltrate both in tumor and in the adjacent thyroid, with final diagnosis of SCC, associated with Hashimoto thyroiditis.
No other primary focus of SCC was found.
Patient has shown a 48-month survival period.
Clinically, primary SCCs of the thyroid and ATCs are similar.
The distinction is often difficult particularly when based on the cytological analysis of FNA material.
American Psychological Association (APA)
Bolfi, Fernanda& Domingues, Maria A. C.& Sobrinho-Simões, Manuel& Soares, Paula& Celestino, Ricardo& Castilho, Emanuel Cellice…[et al.]. 2014. Primary Squamous Cell Carcinoma of the Thyroid Diagnosed as Anaplastic Carcinoma: Failure in Fine-Needle Aspiration Cytology?. Case Reports in Pathology،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1034910
Modern Language Association (MLA)
Bolfi, Fernanda…[et al.]. Primary Squamous Cell Carcinoma of the Thyroid Diagnosed as Anaplastic Carcinoma: Failure in Fine-Needle Aspiration Cytology?. Case Reports in Pathology No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-1034910
American Medical Association (AMA)
Bolfi, Fernanda& Domingues, Maria A. C.& Sobrinho-Simões, Manuel& Soares, Paula& Celestino, Ricardo& Castilho, Emanuel Cellice…[et al.]. Primary Squamous Cell Carcinoma of the Thyroid Diagnosed as Anaplastic Carcinoma: Failure in Fine-Needle Aspiration Cytology?. Case Reports in Pathology. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1034910
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034910