Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group

Abstract EN

Glioneuronal neoplasms are rare tumors.

Recently, an unusual glioneuronal tumor histologically showing neuropil-like islands has been described.

Here, we present such a tumor originating from spinal cord of a 14-year-old girl, who has scoliosis and urinary incontinence.

Microscopically, the glial component was chiefly fibrillary astrocytic, punctuated by neuropil-like islands.

Immunohistochemically, glial tissue was GFAP positive, and neuropil-like areas and big neurons were synaptophysin reactive.

For astrocytic component Ki-67 proliferation index was 1% and p53 was immunonegative.

This case is unique in that in the literature it is the second reported case in pediatric age group that is located at spinal cord.