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Diffuse Hepatic Epithelioid Hemangioendothelioma Developed in a Patient with Hepatitis C Cirrhosis
Joint Authors
Baron, Pedro W.
Amankonah, Thomas
Cubas, Robert F.
Elihu, Arvand
de Vera, Michael E.
Perez, Mia C. N.
Kore, Arputharaj
Source
Case Reports in Transplantation
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-08
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Hepatic epithelioid hemangioendothelioma (HEHE) is an infrequent vascular tumor of endothelial origin that primarily occurs in women in the mid-fifth decade of life without underlying chronic liver disease or cirrhosis.
Liver transplant should be the first-line of therapy in patients with large or diffuse unresectable tumors even in the presence of metastatic disease due to the favorable long-term outcome.
We report the case of a 48-year-old female who complained of abdominal pain and weight loss.
She has a history of cirrhosis secondary to chronic hepatitis C (HCV) and was treated with interferon and ribavirin with sustained virological response.
Her work-up revealed multiple confluent infiltrating bilobar liver masses diagnosed as HEHE.
She underwent a successful liver transplant without evidence of recurrent HCV infection.
She developed cervical spine (C4-C6) HEHE metastases 4 years after transplant.
She underwent surgical resection and local radiotherapy after resection with good clinical response.
To the best of our knowledge, this is the first report of HEHE that developed in a patient with HCV cirrhosis successfully treated with antiviral therapy before transplant and liver transplant with good allograft function without evidence of recurrent liver tumor or HCV infection but developed metastases to the cervical spine 4 years after transplant.
American Psychological Association (APA)
Baron, Pedro W.& Amankonah, Thomas& Cubas, Robert F.& Kore, Arputharaj& Elihu, Arvand& de Vera, Michael E.…[et al.]. 2014. Diffuse Hepatic Epithelioid Hemangioendothelioma Developed in a Patient with Hepatitis C Cirrhosis. Case Reports in Transplantation،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1034996
Modern Language Association (MLA)
Baron, Pedro W.…[et al.]. Diffuse Hepatic Epithelioid Hemangioendothelioma Developed in a Patient with Hepatitis C Cirrhosis. Case Reports in Transplantation No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-1034996
American Medical Association (AMA)
Baron, Pedro W.& Amankonah, Thomas& Cubas, Robert F.& Kore, Arputharaj& Elihu, Arvand& de Vera, Michael E.…[et al.]. Diffuse Hepatic Epithelioid Hemangioendothelioma Developed in a Patient with Hepatitis C Cirrhosis. Case Reports in Transplantation. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1034996
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034996