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Preoperative Serum Levels of Mesothelin in Patients with Colon Cancer
Joint Authors
Battal, Muharrem
Kemık, Ahu S.
Demir, Uygar
Purisa, Sevim
Mihmanlı, Mehmet
Yavuz, Alpaslan
Bostanci, Ozgür
Kemik, Özgür
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-13
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Screening for biochemical markers is important for diagnosing colon cancer.
In this study, the reliability of serum mesothelin levels as a potential diagnostic and screening instrument was evaluated concerning colon cancer.
Methods.
Ninety-five patients who had undergone colonoscopic examination and who were diagnosed with colon cancer were included in the study.
The serum mesothelin levels were measured with the ELISA kits and were evaluated in terms of significant difference when compared between colon cancer and control group.
Results.
Patients with colon cancer had significantly higher mesothelin serum levels ( P < 0.001 ) than the control groups.
We found significant associations between serum levels and tumor grade, perineural invasion, and vascular invasion (resp., P < 0.001 ).
Conclusion.
Evaluating the serum levels of mesothelin has a potential to detect and screen the colon cancer in affected patients.
Our data suggest that mesothelin exhibits effects towards colon cancer and serves as a biomarker for this deadly disease.
American Psychological Association (APA)
Bostanci, Ozgür& Kemik, Özgür& Kemık, Ahu S.& Battal, Muharrem& Demir, Uygar& Purisa, Sevim…[et al.]. 2014. Preoperative Serum Levels of Mesothelin in Patients with Colon Cancer. Disease Markers،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1035047
Modern Language Association (MLA)
Bostanci, Ozgür…[et al.]. Preoperative Serum Levels of Mesothelin in Patients with Colon Cancer. Disease Markers No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1035047
American Medical Association (AMA)
Bostanci, Ozgür& Kemik, Özgür& Kemık, Ahu S.& Battal, Muharrem& Demir, Uygar& Purisa, Sevim…[et al.]. Preoperative Serum Levels of Mesothelin in Patients with Colon Cancer. Disease Markers. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1035047
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035047