![](/images/graphics-bg.png)
Tissue Damage Markers after a Spinal Manipulation in Healthy Subjects: A Preliminary Report of a Randomized Controlled Trial
Joint Authors
Hita-Contreras, F.
Martínez-Amat, A.
Achalandabaso, A.
Plaza-Manzano, G.
Lomas-Vega, R.
Camacho, M. V.
Gassó, M.
Molina, F.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-25
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Spinal manipulation (SM) is a manual therapy technique frequently applied to treat musculoskeletal disorders because of its analgesic effects.
It is defined by a manual procedure involving a directed impulse to move a joint past its physiologic range of movement (ROM).
In this sense, to exceed the physiologic ROM of a joint could trigger tissue damage, which might represent an adverse effect associated with spinal manipulation.
The present work tries to explore the presence of tissue damage associated with SM through the damage markers analysis.
Thirty healthy subjects recruited at the University of Jaén were submitted to a placebo SM (control group; n = 10 ), a single lower cervical manipulation (cervical group; n = 10 ), and a thoracic manipulation ( n = 10 ) .
Before the intervention, blood samples were extracted and centrifuged to obtain plasma and serum.
The procedure was repeated right after the intervention and two hours after the intervention.
Tissue damage markers creatine phosphokinase (CPK), lactate dehydrogenase (LDH), C-reactive protein (CRP), troponin-I, myoglobin, neuron-specific enolase (NSE), and aldolase were determined in samples.
Statistical analysis was performed through a 3 × 3 mixed-model ANOVA.
Neither cervical manipulation nor thoracic manipulation did produce significant changes in the CPK, LDH, CRP, troponin-I, myoglobin, NSE, or aldolase blood levels.
Our data suggest that the mechanical strain produced by SM seems to be innocuous to the joints and surrounding tissues in healthy subjects.
American Psychological Association (APA)
Achalandabaso, A.& Plaza-Manzano, G.& Lomas-Vega, R.& Martínez-Amat, A.& Camacho, M. V.& Gassó, M.…[et al.]. 2014. Tissue Damage Markers after a Spinal Manipulation in Healthy Subjects: A Preliminary Report of a Randomized Controlled Trial. Disease Markers،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1035060
Modern Language Association (MLA)
Achalandabaso, A.…[et al.]. Tissue Damage Markers after a Spinal Manipulation in Healthy Subjects: A Preliminary Report of a Randomized Controlled Trial. Disease Markers No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1035060
American Medical Association (AMA)
Achalandabaso, A.& Plaza-Manzano, G.& Lomas-Vega, R.& Martínez-Amat, A.& Camacho, M. V.& Gassó, M.…[et al.]. Tissue Damage Markers after a Spinal Manipulation in Healthy Subjects: A Preliminary Report of a Randomized Controlled Trial. Disease Markers. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1035060
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035060