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Metabolic Changes and Serum Ghrelin Level in Patients with Psoriasis
Joint Authors
Aydin, Suleyman
Ucak, Haydar
Demir, Betul
Cicek, Demet
Erden, Ilker
Dertlioglu, Selma Bakar
Arica, Mustafa
Source
Dermatology Research and Practice
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-17
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Serum ghrelin levels may be related to metabolic and clinical changes in patients with psoriasis.
Objective.
This study was performed to determine the possible effects of serum ghrelin in patients with psoriasis.
Methods.
The study population consisted of 25 patients with plaque psoriasis.
The patients were questioned with regard to age, gender, age of onset, duration of disease, height, weight, and body mass index (BMI).
In addition, fasting blood sugar, triglyceride, cholesterol levels, insulin, and ghrelin levels were measured.
Results.
The mean serum ghrelin level was 45.41 ± 22.41 in the psoriasis group and 29.92 ± 14.65 in the healthy control group.
Serum ghrelin level was significantly higher in the psoriasis group compared with the controls (P=0.01).
The mean ghrelin level in patients with a lower PASI score was significantly higher than in those with a higher PASI score (P=0.02).
Conclusion.
The present study was performed to determine the effects of ghrelin in psoriasis patients.
We found a negative correlation between severity of psoriasis and ghrelin level.
Larger and especially experimental studies focusing on correlation of immune system-ghrelin levels and severity of psoriasis may be valuable to clarify the etiopathogenesis of the disease.
American Psychological Association (APA)
Ucak, Haydar& Demir, Betul& Cicek, Demet& Erden, Ilker& Aydin, Suleyman& Dertlioglu, Selma Bakar…[et al.]. 2014. Metabolic Changes and Serum Ghrelin Level in Patients with Psoriasis. Dermatology Research and Practice،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1035073
Modern Language Association (MLA)
Ucak, Haydar…[et al.]. Metabolic Changes and Serum Ghrelin Level in Patients with Psoriasis. Dermatology Research and Practice No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1035073
American Medical Association (AMA)
Ucak, Haydar& Demir, Betul& Cicek, Demet& Erden, Ilker& Aydin, Suleyman& Dertlioglu, Selma Bakar…[et al.]. Metabolic Changes and Serum Ghrelin Level in Patients with Psoriasis. Dermatology Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1035073
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035073