Investigation of the Chemical Changes from Crude and Processed Paeoniae Radix Alba-Atractylodis Macrocephalae Rhizoma Herbal Pair Extracts by Using Q Exactive High-Performance Benchtop Quadrupole-Orbitrap LC-MSMS

Joint Authors

Cai, Baochang
Cao, Gang
Cai, Hao
Li, Qinglin
Tu, Sicong

Source

Evidence-Based Complementary and Alternative Medicine

Issue

Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-14, 14 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2014-05-03

Country of Publication

Egypt

No. of Pages

14

Main Subjects

Medicine

Abstract EN

The Paeoniae Radix Alba-Atractylodis Macrocephalae Rhizoma herbal pair is mainly used for regulating the functions of liver and spleen, benefiting qi, and nourishing blood.

However, the bioactive compounds for the pharmacological activities of the crude and processed Paeoniae Radix Alba-Atractylodis Macrocephalae Rhizoma herbal pair extracts are still unclear to date.

In the present study, Q Exactive high-performance benchtop quadrupole-Orbitrap LC-MS/MS was applied to identify the complicated components from crude and processed Paeoniae Radix Alba, crude and processed Atractylodis Macrocephalae Rhizoma, and their crude and processed herbal pair extracts.

123 and 101 compounds were identified in crude and processed Paeoniae Radix Alba samples, respectively.

Meanwhile, 32 and 26 compounds were identified in crude and processed Atractylodis Macrocephalae Rhizoma samples, respectively.

In the crude and processed Paeoniae Radix Alba-Atractylodis Macrocephalae Rhizoma herbal pair extracts, co-decoction could significantly change the chemical composition of Paeoniae Radix Alba and Atractylodis Macrocephalae Rhizoma in solution.

The developed method may provide a scientific foundation for deeply elucidating the processing and compatibility mechanism of Paeoniae Radix Alba and Atractylodis Macrocephalae Rhizoma.

American Psychological Association (APA)

Cao, Gang& Li, Qinglin& Cai, Hao& Tu, Sicong& Cai, Baochang. 2014. Investigation of the Chemical Changes from Crude and Processed Paeoniae Radix Alba-Atractylodis Macrocephalae Rhizoma Herbal Pair Extracts by Using Q Exactive High-Performance Benchtop Quadrupole-Orbitrap LC-MSMS. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-1035116

Modern Language Association (MLA)

Cao, Gang…[et al.]. Investigation of the Chemical Changes from Crude and Processed Paeoniae Radix Alba-Atractylodis Macrocephalae Rhizoma Herbal Pair Extracts by Using Q Exactive High-Performance Benchtop Quadrupole-Orbitrap LC-MSMS. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-1035116

American Medical Association (AMA)

Cao, Gang& Li, Qinglin& Cai, Hao& Tu, Sicong& Cai, Baochang. Investigation of the Chemical Changes from Crude and Processed Paeoniae Radix Alba-Atractylodis Macrocephalae Rhizoma Herbal Pair Extracts by Using Q Exactive High-Performance Benchtop Quadrupole-Orbitrap LC-MSMS. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-1035116

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1035116