Toad Glandular Secretions and Skin Extractions as Anti-Inflammatory and Anticancer Agents
Joint Authors
Hashimi, Saeed M.
Qi, Ji
Tan, C. K.
Wei, Ming Q.
Zulfiker, Abu Hasanat Md.
Good, David
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-06
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Toad glandular secretions and skin extractions contain many natural agents which may provide a unique resource for novel drug development.
The dried secretion from the auricular and skin glands of Chinese toad (Bufo bufo gargarizans) is named Chansu, which has been used in Traditional Chinese Medicine (TCM) for treating infection and inflammation for hundreds of years.
The sterilized hot water extraction of dried toad skin is named Huachansu (Cinobufacini) which was developed for treating hepatitis B virus (HBV) and several types of cancers.
However, the mechanisms of action of Chansu, Huachansu, and their constituents within are not well reported.
Existing studies have suggested that their anti-inflammation and anticancer potential were via targeting Nuclear Factor (NF)- κ B and its signalling pathways which are crucial hallmarks of inflammation and cancer in various experimental models.
Here, we review some current studies of Chansu, Huachansu, and their compounds in terms of their use as both anti-inflammatory and anticancer agents.
We also explored the potential use of toad glandular secretions and skin extractions as alternate resources for treating human cancers in combinational therapies.
American Psychological Association (APA)
Qi, Ji& Tan, C. K.& Hashimi, Saeed M.& Zulfiker, Abu Hasanat Md.& Good, David& Wei, Ming Q.. 2014. Toad Glandular Secretions and Skin Extractions as Anti-Inflammatory and Anticancer Agents. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1035152
Modern Language Association (MLA)
Qi, Ji…[et al.]. Toad Glandular Secretions and Skin Extractions as Anti-Inflammatory and Anticancer Agents. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1035152
American Medical Association (AMA)
Qi, Ji& Tan, C. K.& Hashimi, Saeed M.& Zulfiker, Abu Hasanat Md.& Good, David& Wei, Ming Q.. Toad Glandular Secretions and Skin Extractions as Anti-Inflammatory and Anticancer Agents. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1035152
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035152