Anti-Inflammatory and Antinociceptive Activities of Untreated, Germinated, and Fermented Mung Bean Aqueous Extract
Joint Authors
Alitheen, Noorjahan Banu Mohamed
Beh, Boon Kee
Mohd Ali, Norlaily
Abdullah, Mohd Puad
Koh, Soo Peng
Long, Kamariah
Ho, Wan Yong
Yeap, Swee Keong
Mohd Yusof, Hamidah
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-19
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Evaluation of anti-inflammatory and antinociceptive activities of untreated mung bean (MB), germinated mung bean (GMB), and fermented mung bean (FMB) was performed on both in vitro (inhibition of inflammatory mediator, nitric oxide(NO)) and in vivo (inhibition of ear oedema and reduction of response to pain stimulus) studies.
Results showed that both GMB and FMB aqueous extract exhibited potent anti-inflammatory and antinociceptive activities in a dose-dependent manner.
In vitro results showed that GMB and FMB were potent inflammatory mediator (NO) inhibitors at both 2.5 and 5 mg/mL.
Further in vivo studies showed that GMB and FMB aqueous extract at 1000 mg/kg can significantly reduce ear oedema in mice caused by arachidonic acid.
Besides, both 200 mg/kg and 1000 mg/kg concentrations of GMB and FMB were found to exhibit potent antinociceptive effects towards hotplate induced pain.
With these, it can be concluded that GMB and FMB aqueous extract exhibited potential anti-inflammatory and antinociceptive effects.
American Psychological Association (APA)
Mohd Ali, Norlaily& Mohd Yusof, Hamidah& Yeap, Swee Keong& Ho, Wan Yong& Beh, Boon Kee& Long, Kamariah…[et al.]. 2014. Anti-Inflammatory and Antinociceptive Activities of Untreated, Germinated, and Fermented Mung Bean Aqueous Extract. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1035164
Modern Language Association (MLA)
Mohd Ali, Norlaily…[et al.]. Anti-Inflammatory and Antinociceptive Activities of Untreated, Germinated, and Fermented Mung Bean Aqueous Extract. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1035164
American Medical Association (AMA)
Mohd Ali, Norlaily& Mohd Yusof, Hamidah& Yeap, Swee Keong& Ho, Wan Yong& Beh, Boon Kee& Long, Kamariah…[et al.]. Anti-Inflammatory and Antinociceptive Activities of Untreated, Germinated, and Fermented Mung Bean Aqueous Extract. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1035164
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035164