New Perspectives on Specific Immune-Depletion Technique Using Monoclonal Antibodies against Small Active Molecules in Herbs
Joint Authors
Cheng, Fafeng
Wang, Xueqian
Qu, Hui-Hua
Zhao, Yan
Yu, Cai
Liu, Yuan-Jun
Zhu, Wen-Xiang
Wang, Qingguo
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-17
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
One of the main focuses in Chinese Medicine research is the identification of efficacious components in Chinese herbal medicine (CHM).
Studies in such area are difficult due to the complexity and the synergistic characteristics of CHM.
Current methods to track and separate active components are not adequate to meet the needs of revealing effects and identify substances and pharmacological mechanisms, which directly restrict the modernization and globalization of CHM.
In this paper, a new methodology to deplete a single active component via immunoassay was introduced.
The specific active component in a CHM mixture can then be identified and studied through comparative analyses of the pharmacological effects before and after immune depletion.
With this new methodology, degree of contribution of a particular component to the whole complex herbal mixture can be elucidated, and its synergistic property with other components can be determined.
The new method can reflect not only the overall combined pharmacological effects of CHM but also the effect of individual component.
It is an effective way to explain the degree of contribution of one specific component to the overall activity of a CHM prescription.
American Psychological Association (APA)
Wang, Xueqian& Cheng, Fafeng& Qu, Hui-Hua& Zhao, Yan& Yu, Cai& Liu, Yuan-Jun…[et al.]. 2014. New Perspectives on Specific Immune-Depletion Technique Using Monoclonal Antibodies against Small Active Molecules in Herbs. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1035181
Modern Language Association (MLA)
Wang, Xueqian…[et al.]. New Perspectives on Specific Immune-Depletion Technique Using Monoclonal Antibodies against Small Active Molecules in Herbs. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1035181
American Medical Association (AMA)
Wang, Xueqian& Cheng, Fafeng& Qu, Hui-Hua& Zhao, Yan& Yu, Cai& Liu, Yuan-Jun…[et al.]. New Perspectives on Specific Immune-Depletion Technique Using Monoclonal Antibodies against Small Active Molecules in Herbs. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1035181
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035181