Oxidative stress and immune-suppression in toxoplasma gondi postive blood donors : implications for safe blood transfusion
Joint Authors
Abd al-Nur, Muhammad Fathi
al-Motayam, Muna H.
Mursi, Ayman T. A.
al-Shaykhah, Hani M.
Source
Journal of the Egyptian Society of Parasitology
Issue
Vol. 39, Issue 2 (31 Aug. 2009), pp.421-428, 8 p.
Publisher
The Egyptian Society of Parasitology
Publication Date
2009-08-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Topics
Abstract EN
The sero-markers of Toxoplasma gondii and oxidative stress (OS) were de¬termined in a group of 260 blood donors attending blood banks in Greater Cairo.
Twenty-four blood donors with the highest anti-7! Gondii IgG titer were .
Tested for IgG avidity.
Of whom 4 (16.6%) had low IgG avidity antibodies, documenting recent infection, 6 (25%) had borderline avidity and 14 (58.3%) showed high avidity, ruling out recent infection.
The plasma level of malondialdehyde (MDA) was significantly higher and activity of glutathione peroxides (GSH-Px) and level of tocopherol (a, y, & 6) fractions (P < 0.001) were lower in 7! ^o/zdfa'-seropositive than in seronegative blood donors.
This significant alteration in redox status between seropositive and seronegative do¬nors suggested a degradation of their antioxidant enzymes caused by OS in¬duced by increased free radicals attributable to toxoplasmosis infection.
7! Gondii infection also had a prominent influence on the association between OS biomarkers and immune-suppression status in seropositive donors.
American Psychological Association (APA)
al-Shaykhah, Hani M.& al-Motayam, Muna H.& Abd al-Nur, Muhammad Fathi& Mursi, Ayman T. A.. 2009. Oxidative stress and immune-suppression in toxoplasma gondi postive blood donors : implications for safe blood transfusion. Journal of the Egyptian Society of Parasitology،Vol. 39, no. 2, pp.421-428.
https://search.emarefa.net/detail/BIM-103521
Modern Language Association (MLA)
al-Shaykhah, Hani M.…[et al.]. Oxidative stress and immune-suppression in toxoplasma gondi postive blood donors : implications for safe blood transfusion. Journal of the Egyptian Society of Parasitology Vol. 39, no. 2 (Aug. 2009), pp.421-428.
https://search.emarefa.net/detail/BIM-103521
American Medical Association (AMA)
al-Shaykhah, Hani M.& al-Motayam, Muna H.& Abd al-Nur, Muhammad Fathi& Mursi, Ayman T. A.. Oxidative stress and immune-suppression in toxoplasma gondi postive blood donors : implications for safe blood transfusion. Journal of the Egyptian Society of Parasitology. 2009. Vol. 39, no. 2, pp.421-428.
https://search.emarefa.net/detail/BIM-103521
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 426-428
Record ID
BIM-103521