Effect of Eugenol on Cell Surface Hydrophobicity, Adhesion, and Biofilm of Candida tropicalis and Candida dubliniensis Isolated from Oral Cavity of HIV-Infected Patients
Joint Authors
Nakamura, Celso Vataru
de Paula, Suelen Balero
Bartelli, Thais Fernanda
Di Raimo, Vanessa
Santos, Jussevania Pereira
Morey, Alexandre Tadachi
Bosini, Marina Andrea
Yamauchi, Lucy Megumi
Yamada-Ogatta, Sueli Fumie
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-03
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Most Candida spp.
infections are associated with biofilm formation on host surfaces.
Cells within these communities display a phenotype resistant to antimicrobials and host defenses, so biofilm-associated infections are difficult to treat, representing a source of reinfections.
The present study evaluated the effect of eugenol on the adherence properties and biofilm formation capacity of Candida dubliniensis and Candida tropicalis isolated from the oral cavity of HIV-infected patients.
All isolates were able to form biofilms on different substrate surfaces.
Eugenol showed inhibitory activity against planktonic and sessile cells of Candida spp.
No metabolic activity in biofilm was detected after 24 h of treatment.
Scanning electron microscopy demonstrated that eugenol drastically reduced the number of sessile cells on denture material surfaces.
Most Candida species showed hydrophobic behavior and a significant difference in cell surface hydrophobicity was observed after exposure of planktonic cells to eugenol for 1 h.
Eugenol also caused a significant reduction in adhesion of most Candida spp.
to HEp-2 cells and to polystyrene.
These findings corroborate the effectiveness of eugenol against Candida species other than C.
albicans, reinforcing its potential as an antifungal applied to limit both the growth of planktonic cells and biofilm formation on different surfaces.
American Psychological Association (APA)
de Paula, Suelen Balero& Bartelli, Thais Fernanda& Di Raimo, Vanessa& Santos, Jussevania Pereira& Morey, Alexandre Tadachi& Bosini, Marina Andrea…[et al.]. 2014. Effect of Eugenol on Cell Surface Hydrophobicity, Adhesion, and Biofilm of Candida tropicalis and Candida dubliniensis Isolated from Oral Cavity of HIV-Infected Patients. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1035239
Modern Language Association (MLA)
de Paula, Suelen Balero…[et al.]. Effect of Eugenol on Cell Surface Hydrophobicity, Adhesion, and Biofilm of Candida tropicalis and Candida dubliniensis Isolated from Oral Cavity of HIV-Infected Patients. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1035239
American Medical Association (AMA)
de Paula, Suelen Balero& Bartelli, Thais Fernanda& Di Raimo, Vanessa& Santos, Jussevania Pereira& Morey, Alexandre Tadachi& Bosini, Marina Andrea…[et al.]. Effect of Eugenol on Cell Surface Hydrophobicity, Adhesion, and Biofilm of Candida tropicalis and Candida dubliniensis Isolated from Oral Cavity of HIV-Infected Patients. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1035239
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035239