Antifungal Activity of Decyl Gallate against Several Species of Pathogenic Fungi
Joint Authors
Gullo, Fernanda P.
Sangalli-Leite, Fernanda
Pitangui, Nayla S.
Fusco-Almeida, Ana Marisa
de Paula e Silva, Ana Carolina Alves
Costa-Orlandi, Caroline Barcelos
de Oliveira, Haroldo Cesar
Silva, Julhiany de Fátima da
Scorzoni, Liliana
Rossi, Suélen Andrea
Benaducci, Tatiane
Wolf, Vanessa Gonçalves
Regasini, Luis Octávio
Petrônio, Maicon Segalla
Silva, Dulce Helena Siqueira
Bolzani, Vanderlan S.
Mendes-Giannini, Maria José Soares
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
This work aims to demonstrate that the gallic acid structure modification to the decyl gallate (G14) compound contributed to increase the antifungal activity against several species of pathogenic fungi, mainly, Candida spp., Cryptococcus spp., Paracoccidioides spp., and Histoplasma capsulatum, according to standardized microdilution method described by Clinical Laboratory Standard Institute (CLSI) documents.
Moreover this compound has a particularly good selectivity index value, which makes it an excellent candidate for broad-spectrum antifungal prototype and encourages the continuation of subsequent studies for the discovery of its mechanism of action.
American Psychological Association (APA)
de Paula e Silva, Ana Carolina Alves& Costa-Orlandi, Caroline Barcelos& Gullo, Fernanda P.& Sangalli-Leite, Fernanda& de Oliveira, Haroldo Cesar& Silva, Julhiany de Fátima da…[et al.]. 2014. Antifungal Activity of Decyl Gallate against Several Species of Pathogenic Fungi. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1035243
Modern Language Association (MLA)
de Paula e Silva, Ana Carolina Alves…[et al.]. Antifungal Activity of Decyl Gallate against Several Species of Pathogenic Fungi. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1035243
American Medical Association (AMA)
de Paula e Silva, Ana Carolina Alves& Costa-Orlandi, Caroline Barcelos& Gullo, Fernanda P.& Sangalli-Leite, Fernanda& de Oliveira, Haroldo Cesar& Silva, Julhiany de Fátima da…[et al.]. Antifungal Activity of Decyl Gallate against Several Species of Pathogenic Fungi. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1035243
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035243