Quality Control of Danggui Buxue Tang, a Traditional Chinese Medicine Decoction, by 1H-NMR Metabolic Profiling
Joint Authors
Chan, Pui Hei
Cheung, Chi Yuen
Lam, Henry
Zhang, Wendy L.
Tsim, Karl Wah-Keung
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-23
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Danggui Buxue Tang (DBT) is one of the simplest traditional Chinese medicine (TCM) decoctions, first described in China in 1247 AD.
DBT is composed of 2 herbs, Astragali Radix (AR) and Angelica Sinensis Radix (ASR), boiled together in a 5 : 1 ratio.
Clinically, DBT is prescribed to women as a remedy for menopausal symptoms.
Here, 1H-NMR metabolic profiling was conducted for DBT and the water extracts of AR or ASR, to evaluate the potential of this chemical profiling method for quality control of the herbal decoction.
Principal component analysis (PCA) showed that DBT could be readily distinguished from the water extracts of its constituent herbs by the metabolic profiles.
More interestingly, the metabolic profile of DBT was not a simple sum of that of AR and ASR.
Asparagine was found at significantly higher concentration in DBT than that in either AR or ASR extract, contributing mainly to the discrimination of DBT sample.
In addition, we employed the same method to profile a commercial DBT powder, verifying its authenticity as compared to our prepared DBT.
This study is the first to employ 1H-NMR metabolic profiling for the quality control of traditional Chinese medicine decoctions.
American Psychological Association (APA)
Chan, Pui Hei& Zhang, Wendy L.& Cheung, Chi Yuen& Tsim, Karl Wah-Keung& Lam, Henry. 2014. Quality Control of Danggui Buxue Tang, a Traditional Chinese Medicine Decoction, by 1H-NMR Metabolic Profiling. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1035281
Modern Language Association (MLA)
Chan, Pui Hei…[et al.]. Quality Control of Danggui Buxue Tang, a Traditional Chinese Medicine Decoction, by 1H-NMR Metabolic Profiling. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1035281
American Medical Association (AMA)
Chan, Pui Hei& Zhang, Wendy L.& Cheung, Chi Yuen& Tsim, Karl Wah-Keung& Lam, Henry. Quality Control of Danggui Buxue Tang, a Traditional Chinese Medicine Decoction, by 1H-NMR Metabolic Profiling. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1035281
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035281