Cytotoxicity of Aporphine, Protoberberine, and Protopine Alkaloids from Dicranostigma leptopodum (Maxim.) Fedde
Joint Authors
Sun, Ruiqi
Jiang, Haiyan
Zhang, Wenjuan
Yang, Kai
Wang, Chengfang
Fan, Li
He, Qing
Feng, Jiangbin
Deng, Zhiwei
Geng, Zhufeng
Du, Shu Shan
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-21
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Nine alkaloids with three different structural skeletons were isolated from Dicranostigma leptopodum (Maxim.) Fedde (Papaveraceae) by repeated silica gel column chromatography.
Their chemical structures were identified on the basic of physicochemical and spectroscopic data.
Among them, 10-O-methylhernovine (1), nantenine (2), corytuberine (3), lagesianine A (4), and dihydrocryptopine (9) were first isolated from this plant.
With a series of cytotoxic tests, compounds 2, 3, and 7 displayed cytotoxicity against SMMC-7721 with IC50 values of 70.08 ± 4.63, 73.22 ± 2.35, and 27.77 ± 2.29 μM, respectively.
American Psychological Association (APA)
Sun, Ruiqi& Jiang, Haiyan& Zhang, Wenjuan& Yang, Kai& Wang, Chengfang& Fan, Li…[et al.]. 2014. Cytotoxicity of Aporphine, Protoberberine, and Protopine Alkaloids from Dicranostigma leptopodum (Maxim.) Fedde. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1035289
Modern Language Association (MLA)
Sun, Ruiqi…[et al.]. Cytotoxicity of Aporphine, Protoberberine, and Protopine Alkaloids from Dicranostigma leptopodum (Maxim.) Fedde. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1035289
American Medical Association (AMA)
Sun, Ruiqi& Jiang, Haiyan& Zhang, Wenjuan& Yang, Kai& Wang, Chengfang& Fan, Li…[et al.]. Cytotoxicity of Aporphine, Protoberberine, and Protopine Alkaloids from Dicranostigma leptopodum (Maxim.) Fedde. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1035289
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035289
