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Chinese Medicine Shensongyangxin Is Effective for Patients with Bradycardia: Results of a Randomized, Double-Blind, Placebo-Controlled Multicenter Trial
Joint Authors
Li, Ning
Jia, Zhenhua
Lu, Feng
Pu, Jielin
Liu, Yunfang
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
To evaluate the efficacy and safety of Shensong Yangxin (SSYX) in patients with bradycardia arrhythmias, a randomized, double-blind, and placebo-controlled study was conducted.
Patients with bradycardia were randomly assigned to receive either SSYX (trial group, n = 115 ) or placebo (control group, n = 104 ) for 4 weeks.
ECG, 24-hour continuous ECG recording, echocardiography, and hepatic and renal function were evaluated at baseline and after treatment.
Results showed that the average heart rate, the fastest heart rate, and the lowest heart rate in the trial group were all significantly higher than those in the control group at the end of treatment ( P < 0.05 or 0.01, resp.).
Compared with pretreatment, the average heart rate, the fastest heart rate, and the lowest heart rate in the trial group all increased significantly after treatment ( P < 0.05 or 0.01, resp.).
Both the efficacy and the symptom scores in the trial group were significantly better than those in the control group after treatment (both having P < 0.0 1 ).
No severe adverse effects were reported.
In conclusion, SSYX treatment significantly increased the heart rate in patients with bradycardia without severe side effects.
The exact mechanisms remain to be further explored.
American Psychological Association (APA)
Liu, Yunfang& Li, Ning& Jia, Zhenhua& Lu, Feng& Pu, Jielin. 2013. Chinese Medicine Shensongyangxin Is Effective for Patients with Bradycardia: Results of a Randomized, Double-Blind, Placebo-Controlled Multicenter Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1035298
Modern Language Association (MLA)
Liu, Yunfang…[et al.]. Chinese Medicine Shensongyangxin Is Effective for Patients with Bradycardia: Results of a Randomized, Double-Blind, Placebo-Controlled Multicenter Trial. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1035298
American Medical Association (AMA)
Liu, Yunfang& Li, Ning& Jia, Zhenhua& Lu, Feng& Pu, Jielin. Chinese Medicine Shensongyangxin Is Effective for Patients with Bradycardia: Results of a Randomized, Double-Blind, Placebo-Controlled Multicenter Trial. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1035298
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035298