Hydrolysis of Glycosidic Flavonoids during the Preparation of Danggui Buxue Tang: An Outcome of Moderate Boiling of Chinese Herbal Mixture
Joint Authors
Chen, Jianping
Zhan, Janis Ya-xian
Lam, Kelly Yin-Ching
Zhang, Wendy L.
Dong, Tina Ting-Xia
Tsim, Karl Wah-Keung
Yao, Ping
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-16
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Chemical change during boiling of herbal mixture is a puzzle.
By using Danggui Buxue Tang (DBT), a herbal decoction that contains Astragali Radix (AR) and Angelicae Sinensis Radix (ASR), we developed a model in analyzing the hydrolysis of flavonoid glycosides during the boiling of herbal mixture in water.
A proper preparation of DBT is of great benefit to the complete extraction of bioactive ingredients.
Boiling of DBT in water increased the solubility of AR-derived astragaloside IV, calycosin, formononetin, calycosin-7-O-β-D-glucoside, and ononin in a time- and temperature-dependent manner: the amounts of these chemicals reached a peak at 2 h.
The glycosidic resides of AR, calycosin-7-O-β-D-glucoside, and ononin could be hydrolyzed during the moderate boiling process to form calycosin and formononetin, respectively.
The hydrolysis efficiency was strongly affected by pH, temperature, and amount of herbs.
Interestingly, the preheated herbs were not able to show this hydrolytic activity.
The current results supported the rationality of ancient preparation of DBT in boiling water by moderate heat.
American Psychological Association (APA)
Zhang, Wendy L.& Chen, Jianping& Lam, Kelly Yin-Ching& Zhan, Janis Ya-xian& Yao, Ping& Dong, Tina Ting-Xia…[et al.]. 2014. Hydrolysis of Glycosidic Flavonoids during the Preparation of Danggui Buxue Tang: An Outcome of Moderate Boiling of Chinese Herbal Mixture. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1035300
Modern Language Association (MLA)
Zhang, Wendy L.…[et al.]. Hydrolysis of Glycosidic Flavonoids during the Preparation of Danggui Buxue Tang: An Outcome of Moderate Boiling of Chinese Herbal Mixture. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1035300
American Medical Association (AMA)
Zhang, Wendy L.& Chen, Jianping& Lam, Kelly Yin-Ching& Zhan, Janis Ya-xian& Yao, Ping& Dong, Tina Ting-Xia…[et al.]. Hydrolysis of Glycosidic Flavonoids during the Preparation of Danggui Buxue Tang: An Outcome of Moderate Boiling of Chinese Herbal Mixture. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1035300
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035300