Neuronal Activity Stimulated by Liquid Substrates Injection at Zusanli (ST36) Acupoint: The Possible Mechanism of Aquapuncture
Joint Authors
Chern, Rey-Shyong
Chien, Chi-Hsien
Lin, Chao-Nan
Tsai, Yu-Chuan
Chang, Yung-Hsien
Chen, Chun-Yen
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-06
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Aquapuncture is a modified acupuncture technique and it is generally accepted that it has a greater therapeutic effect than acupuncture because of the combination of the acupoint stimulation and the pharmacological effect of the drugs.
However, to date, the mechanisms underlying the effects of aquapuncture remain unclear.
We hypothesized that both the change in the local spatial configuration and the substrate stimulation of aquapuncture would activate neuronal signaling.
Thus, bee venom, normal saline, and vitamins B1 and B12 were injected into a Zusanli (ST36) acupoint as substrate of aquapuncture, whereas a dry needle was inserted into ST36 as a control.
After aquapuncture, activated neurons expressing Fos protein were mainly observed in the dorsal horn of the spinal cord in lumbar segments L3–5, with the distribution nearly identical among all groups.
However, the bee venom injection induced significantly more Fos-expressing neurons than the other substrates.
Based on these data, we suggest that changes in the spatial configuration of the acupoint activate neuronal signaling and that bee venom may further strengthen this neuronal activity.
In conclusion, the mechanisms for the effects of aquapuncture appear to be the spatial configuration changes occurring within the acupoint and the ability of injected substrates to stimulate neuronal activity.
American Psychological Association (APA)
Chen, Chun-Yen& Lin, Chao-Nan& Chern, Rey-Shyong& Tsai, Yu-Chuan& Chang, Yung-Hsien& Chien, Chi-Hsien. 2014. Neuronal Activity Stimulated by Liquid Substrates Injection at Zusanli (ST36) Acupoint: The Possible Mechanism of Aquapuncture. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1035311
Modern Language Association (MLA)
Chen, Chun-Yen…[et al.]. Neuronal Activity Stimulated by Liquid Substrates Injection at Zusanli (ST36) Acupoint: The Possible Mechanism of Aquapuncture. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1035311
American Medical Association (AMA)
Chen, Chun-Yen& Lin, Chao-Nan& Chern, Rey-Shyong& Tsai, Yu-Chuan& Chang, Yung-Hsien& Chien, Chi-Hsien. Neuronal Activity Stimulated by Liquid Substrates Injection at Zusanli (ST36) Acupoint: The Possible Mechanism of Aquapuncture. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1035311
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035311