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Therapeutic Implications of Black Seed and Its Constituent Thymoquinone in the Prevention of Cancer through Inactivation and Activation of Molecular Pathways
Joint Authors
Rahmani, Arshad H.
Aly, Salah M.
Khan, Masood A.
Alzohairy, Mohammad A.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-18
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
The cancer is probably the most dreaded disease in both men and women and also major health problem worldwide.
Despite its high prevalence, the exact molecular mechanisms of the development and progression are not fully understood.
The current chemotherapy/radiotherapy regime used to treat cancer shows adverse side effect and may alter gene functions.
Natural products are generally safe, effective, and less expensive substitutes of anticancer chemotherapeutics.
Based on previous studies of their potential therapeutic uses, Nigella sativa and its constituents may be proved as good therapeutic options in the prevention of cancer.
Black seeds are used as staple food in the Middle Eastern Countries for thousands of years and also in the treatment of diseases.
Earlier studies have shown that N.
sativa and its constituent thymoquinone (TQ) have important roles in the prevention and treatment of cancer by modulating cell signaling pathways.
In this review, we summarize the role of N.
sativa and its constituents TQ in the prevention of cancer through the activation or inactivation of molecular cell signaling pathways.
American Psychological Association (APA)
Rahmani, Arshad H.& Alzohairy, Mohammad A.& Khan, Masood A.& Aly, Salah M.. 2014. Therapeutic Implications of Black Seed and Its Constituent Thymoquinone in the Prevention of Cancer through Inactivation and Activation of Molecular Pathways. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-1035351
Modern Language Association (MLA)
Rahmani, Arshad H.…[et al.]. Therapeutic Implications of Black Seed and Its Constituent Thymoquinone in the Prevention of Cancer through Inactivation and Activation of Molecular Pathways. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-13.
https://search.emarefa.net/detail/BIM-1035351
American Medical Association (AMA)
Rahmani, Arshad H.& Alzohairy, Mohammad A.& Khan, Masood A.& Aly, Salah M.. Therapeutic Implications of Black Seed and Its Constituent Thymoquinone in the Prevention of Cancer through Inactivation and Activation of Molecular Pathways. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-1035351
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035351