Antioxidant and Antiadipogenic Activities of Galkeun-Tang, a Traditional Korean Herbal Formula
Joint Authors
Shin, Hyeun-Kyoo
Seo, Chang-Seob
Yoo, Sae-Rom
Kim, Ohn-Soon
Jeong, Soo-Jin
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-10
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Galkeun-tang (GKT; Galgen-tang in Chinese and Kakkon-to in Japanese), a traditional herbal formula, has been used for treatment of the common cold.
Here, we report in vitro antioxidant and antiadipogenic effects of GKT.
GKT increased the activities of scavenging 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals.
GKT also significantly reduced the malondialdehyde (MDA) generation during low-density lipoprotein (LDL) oxidation and the electrophoretic mobility of oxidized LDL, indicating inhibitory effects of GKT on Cu2+-mediated oxidation of LDL.
Regarding antiadipogenic activity, GKT treatment significantly suppressed lipid accumulation, triglyceride production, and glycerol-3-phosphate dehydrogenase (GPDH) activity in differentiated 3T3-L1 adipocytes.
Consistent with this, GKT significantly reduced the secretion of leptin, a major adipokine, in differentiated 3T3-L1 adipocytes.
Overall, our findings suggest that GKT has the potential for antioxidative and antiadipogenic properties.
American Psychological Association (APA)
Jeong, Soo-Jin& Yoo, Sae-Rom& Kim, Ohn-Soon& Seo, Chang-Seob& Shin, Hyeun-Kyoo. 2014. Antioxidant and Antiadipogenic Activities of Galkeun-Tang, a Traditional Korean Herbal Formula. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1035361
Modern Language Association (MLA)
Jeong, Soo-Jin…[et al.]. Antioxidant and Antiadipogenic Activities of Galkeun-Tang, a Traditional Korean Herbal Formula. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1035361
American Medical Association (AMA)
Jeong, Soo-Jin& Yoo, Sae-Rom& Kim, Ohn-Soon& Seo, Chang-Seob& Shin, Hyeun-Kyoo. Antioxidant and Antiadipogenic Activities of Galkeun-Tang, a Traditional Korean Herbal Formula. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1035361
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035361