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Synergistic Effect of Fermented Rice Extracts on the Probiotic and Laxative Properties of Yoghurt in Rats with Loperamide-Induced Constipation
Joint Authors
Kim, Ki-Young
Choi, Jae-Suk
Kim, Joo Wan
Lee, Jong-Kwang
Sohn, Jae Hak
Ku, Sae-Kwang
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-20
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Aim.
The objective was to evaluate the synergistic effects of fermented rice extracts (FRe) on the laxative and probiotic properties of yoghurt in rats with loperamide-induced constipation.
Methods.
After constipation induction, yoghurt containing FRe (BFRe; 0.05%, 0.1%, or 1%) was administered orally once per day for 6 days.
Results.
Loperamide treatment caused marked decreases in fecal pellet numbers and water content discharged, as well as in the surface mucosal thickness of the colonic lumen, intestinal charcoal transit ratio, thickness, and number of mucous-producing goblet cells in the colonic mucosa, whereas it increased the remnant fecal pellet number and the mean diameter of the colonic lumen.
However, this loperamide-induced constipation was ameliorated by treatment with FRe, yoghurt single formula, or 0.05%, 0.1%, or 1% BFRe (10 mL/kg).
Additionally, the viable numbers of Lactobacillus in the cecal contents and feces were markedly higher than those in constipated rats.
Moreover, greater probiotic and laxative effects were detected in BFRe-treated rats than in rats treated with equivalent doses of yoghurt or FRe single formula.
Conclusion.
The results suggest that addition of FRe to liquid yoghurt will enhance the probiotic and beneficial laxative effects of yoghurt in the digestive tract, without causing side effects.
American Psychological Association (APA)
Choi, Jae-Suk& Kim, Joo Wan& Kim, Ki-Young& Lee, Jong-Kwang& Sohn, Jae Hak& Ku, Sae-Kwang. 2014. Synergistic Effect of Fermented Rice Extracts on the Probiotic and Laxative Properties of Yoghurt in Rats with Loperamide-Induced Constipation. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1035434
Modern Language Association (MLA)
Choi, Jae-Suk…[et al.]. Synergistic Effect of Fermented Rice Extracts on the Probiotic and Laxative Properties of Yoghurt in Rats with Loperamide-Induced Constipation. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-1035434
American Medical Association (AMA)
Choi, Jae-Suk& Kim, Joo Wan& Kim, Ki-Young& Lee, Jong-Kwang& Sohn, Jae Hak& Ku, Sae-Kwang. Synergistic Effect of Fermented Rice Extracts on the Probiotic and Laxative Properties of Yoghurt in Rats with Loperamide-Induced Constipation. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1035434
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035434