Effects of Acupuncture Knife on Inflammatory Factors and Pain in Third Lumbar Vertebrae Transverse Process Syndrome Model Rats
Joint Authors
Xu, Hong
Yu, Jia Ni
Guo, Chang Qing
Hu, Bo
Liu, Nai Gang
Sun, Hong Mei
Wu, Hai Xia
Guo, Yan
Liang, Chu Xi
Chen, Zhan Xia
Li, Xiao-Hong
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-02
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The aim of this paper was to explore the long-term effects and pain relief mechanism of acupuncture knife on third lumbar vertebrae (L3) transverse process syndrome.
Forty SD rats were randomized into control, model, electroacupuncture (EA), and acupuncture knife (AK) group.
Except control rats, other rats were subjected to an operation to emulate L3 transverse process syndrome.
Fourteen days after the operation, EA and AK rats were given electroacupuncture and acupuncture knife treatments, respectively.
Fifty-six days after the operation, enzyme-linked immunosorbent assay was used to measure substance P (SP), 5-hydroxytryptamine (5-HT), interleukin-1β (IL-1β), interleukin-10 (IL-10), tumor necrosis factor-α (TNF-α), and transforming growth factor-β (TGF-β) in peripheral blood.
The tail flick test was used to observe pain threshold.
We found that rats with the simulation operation had significantly higher levels of SP, 5-HT, IL-1, IL-10, TNF-α, and TGF-β, while the AK rats had lower levels.
In addition, the pain threshold of AK rats was similar to that of control rats.
AK pretreatment could alleviate pain through modulating inflammatory response.
American Psychological Association (APA)
Yu, Jia Ni& Guo, Chang Qing& Hu, Bo& Liu, Nai Gang& Sun, Hong Mei& Xu, Hong…[et al.]. 2014. Effects of Acupuncture Knife on Inflammatory Factors and Pain in Third Lumbar Vertebrae Transverse Process Syndrome Model Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1035438
Modern Language Association (MLA)
Yu, Jia Ni…[et al.]. Effects of Acupuncture Knife on Inflammatory Factors and Pain in Third Lumbar Vertebrae Transverse Process Syndrome Model Rats. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1035438
American Medical Association (AMA)
Yu, Jia Ni& Guo, Chang Qing& Hu, Bo& Liu, Nai Gang& Sun, Hong Mei& Xu, Hong…[et al.]. Effects of Acupuncture Knife on Inflammatory Factors and Pain in Third Lumbar Vertebrae Transverse Process Syndrome Model Rats. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1035438
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035438