Electroacupuncture Ameliorates Acute Lung Injury through Promoting Gastrointestinal Motility in Rats with Acute Pancreatitis
Joint Authors
Zhu, Shi-Feng
Zhao, Xian-Lin
Wan, Mei-Hua
Tang, Wen-Fu
Guo, Hui
Zhang, Rong-Rong
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-27
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
Gastrointestinal disfunction and acute lung injury (ALI) were common in acute pancreatitis (AP).
The effect of electro-acupuncture (EA) on gastrointestinal motility and ALI in rats with AP was investigated to verify the theory of “lung and large intestine are interior exteriorly related” in traditional Chinese medicine.
Methods.
Male Sprague-Dawley rats were randomly divided into the normal group, model group, and EA group.
AP model was established by three injections of 20% L-arginine at 1 h intervals.
EA were applied to bilateral ST-25 and ST-36 for 30 minutes twice a day after modeling for 3 days.
Arterial blood, pancreas, lung, and intestinal tissues were collected for detecting the inflammatory factors and histopathology.
Intestinal propulsion rate (IPR) was also measured at 72 h.
Results.
EA treatment improved IPR and increased CCK-8 level compared with model group (P < 0.05).
It lowered the serum levels of TNF-α and IL-6 and increased the level of IL-4 with no effect on IL-10.
EA treatment reduced serum vasoactive intestinal peptide (VIP) and myeloperoxidase (MPO) level in the lung and the pathologic scores of pancreas, lung and intestine were decreased (P < 0.05).
Conclusion.
EA treatment could promote gastrointestinal motility through inhibiting VIP, and promoting CCK expression and regulate pro- and anti-inflammatory mediators to ameliorate ALI in AP.
American Psychological Association (APA)
Guo, Hui& Zhu, Shi-Feng& Zhang, Rong-Rong& Zhao, Xian-Lin& Wan, Mei-Hua& Tang, Wen-Fu. 2014. Electroacupuncture Ameliorates Acute Lung Injury through Promoting Gastrointestinal Motility in Rats with Acute Pancreatitis. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1035470
Modern Language Association (MLA)
Guo, Hui…[et al.]. Electroacupuncture Ameliorates Acute Lung Injury through Promoting Gastrointestinal Motility in Rats with Acute Pancreatitis. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1035470
American Medical Association (AMA)
Guo, Hui& Zhu, Shi-Feng& Zhang, Rong-Rong& Zhao, Xian-Lin& Wan, Mei-Hua& Tang, Wen-Fu. Electroacupuncture Ameliorates Acute Lung Injury through Promoting Gastrointestinal Motility in Rats with Acute Pancreatitis. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1035470
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035470