The Effect of the Kampo Medicine Yokukansan on Preoperative Anxiety and Sedation Levels
Joint Authors
Nishihara, Makoto
Maruyama, Yuki
Ito, Akihiro
Ikemoto, Tatsunori
Kawai, Takashi
Sueoka, Satoshi
Banno, Shinya
Takayama, Hitomi
Tawada, Yusuke
Sakakima, Yoshikazu
Kawanishi, Jun
Arai, Young-Chang P.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-30
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Preoperative anxiety can lead to unfavorable physiological response such as tachycardia and hypertension.
Prevention of preoperative anxiety improves surgical outcome and decreases inpatient stay.
Yokukansan is one of prescriptions in Kampo, traditional Japanese herbal medicine, and is known to exert anxiolytic effects.
The aim of the present study was to compare the effects of diazepam and Yokukansan on preoperative anxiety, salivary amylase activity, and sedation levels.
Methods.
Seventy American Society of Anesthesiologists physical status I or II patients presenting for hemicolectomy under general anesthesia combined with epidural anesthesia were enrolled.
The Diazepam group received diazepam 5 mg orally and the Yokukansan group received Yokukansan 2.5 g orally.
Results.
Although levels of anxiety and salivary amylase activity were not different between the two groups, the modified Observer’s Assessment of Alertness/Sedation Scale of the Yokukansan group was significantly higher compared to that of the Diazepam group.
Conclusion.
Yokukansan alleviated preoperative anxiety without undesirable sedation, when compared with diazepam.
American Psychological Association (APA)
Arai, Young-Chang P.& Kawanishi, Jun& Sakakima, Yoshikazu& Sueoka, Satoshi& Ito, Akihiro& Tawada, Yusuke…[et al.]. 2014. The Effect of the Kampo Medicine Yokukansan on Preoperative Anxiety and Sedation Levels. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1035500
Modern Language Association (MLA)
Arai, Young-Chang P.…[et al.]. The Effect of the Kampo Medicine Yokukansan on Preoperative Anxiety and Sedation Levels. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-1035500
American Medical Association (AMA)
Arai, Young-Chang P.& Kawanishi, Jun& Sakakima, Yoshikazu& Sueoka, Satoshi& Ito, Akihiro& Tawada, Yusuke…[et al.]. The Effect of the Kampo Medicine Yokukansan on Preoperative Anxiety and Sedation Levels. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1035500
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035500