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Evaluation of Traditional Medicines for Neurodegenerative Diseases Using Drosophila Models
Joint Authors
Lee, Soojin
Bang, Se Min
Lee, Joon Woo
Cho, Kyoung Sang
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-26
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Drosophila is one of the oldest and most powerful genetic models and has led to novel insights into a variety of biological processes.
Recently, Drosophila has emerged as a model system to study human diseases, including several important neurodegenerative diseases.
Because of the genomic similarity between Drosophila and humans, Drosophila neurodegenerative disease models exhibit a variety of human-disease-like phenotypes, facilitating fast and cost-effective in vivo genetic modifier screening and drug evaluation.
Using these models, many disease-associated genetic factors have been identified, leading to the identification of compelling drug candidates.
Recently, the safety and efficacy of traditional medicines for human diseases have been evaluated in various animal disease models.
Despite the advantages of the Drosophila model, its usage in the evaluation of traditional medicines is only nascent.
Here, we introduce the Drosophila model for neurodegenerative diseases and some examples demonstrating the successful application of Drosophila models in the evaluation of traditional medicines.
American Psychological Association (APA)
Lee, Soojin& Bang, Se Min& Lee, Joon Woo& Cho, Kyoung Sang. 2014. Evaluation of Traditional Medicines for Neurodegenerative Diseases Using Drosophila Models. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-1035503
Modern Language Association (MLA)
Lee, Soojin…[et al.]. Evaluation of Traditional Medicines for Neurodegenerative Diseases Using Drosophila Models. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-1035503
American Medical Association (AMA)
Lee, Soojin& Bang, Se Min& Lee, Joon Woo& Cho, Kyoung Sang. Evaluation of Traditional Medicines for Neurodegenerative Diseases Using Drosophila Models. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-1035503
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035503