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American Ginseng Extract (Panax quinquefolius L.) Is Safe in Long-Term Use in Type 2 Diabetic Patients
Joint Authors
Mucalo, Iva
Jovanovski, Elena
Vuksan, Vladimir
Božikov, Velimir
Romić, Željko
Rahelić, Dario
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-07
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aim.
The objective of the present study was to test the safety of supplementation with the American ginseng (AG) interventional material as an adjunct to conventional therapy (diet and/or medications) in type 2 diabetes, using a double-blind, randomized, placebo-controlled, parallel design.
Methods.
Each participant received either AG (10% ginsenosides) or placebo capsules (500 mg/meal = 3 g/day) for a period of 12 weeks.
Outcomes included measures of safety including kidney function (urates and creatinine), liver function (AST and ALT), and haemostatic function (PV and INR).
Results.
Seventy-four participants with well-controlled type 2 diabetes (sex: 28 M and 46 F, age: 63 ± 9.5, BMI: 32 ± 5, and HbA1c: 7 ± 1.3), randomized to either intervention (n=35) or control (n=39) group, completed the study.
There was no change in any of the measures of safety between treatments from baseline.
The number or severity of adverse events did not differ between the AG intervention and placebo.
Conclusion.
Following 12 weeks of supplementation with AG, safety was not compromised in a high cardiovascular disease (CVD) risk population of patients with type 2 diabetes.
This demonstrated that safety is noteworthy, as reviews have continuously warned of possible adverse effects of ginseng consumption.
American Psychological Association (APA)
Mucalo, Iva& Jovanovski, Elena& Vuksan, Vladimir& Božikov, Velimir& Romić, Željko& Rahelić, Dario. 2014. American Ginseng Extract (Panax quinquefolius L.) Is Safe in Long-Term Use in Type 2 Diabetic Patients. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1035504
Modern Language Association (MLA)
Mucalo, Iva…[et al.]. American Ginseng Extract (Panax quinquefolius L.) Is Safe in Long-Term Use in Type 2 Diabetic Patients. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1035504
American Medical Association (AMA)
Mucalo, Iva& Jovanovski, Elena& Vuksan, Vladimir& Božikov, Velimir& Romić, Željko& Rahelić, Dario. American Ginseng Extract (Panax quinquefolius L.) Is Safe in Long-Term Use in Type 2 Diabetic Patients. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1035504
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035504