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Xanthogranulomatous Cholecystitis Masquerading as Gallbladder Cancer: Can It Be Diagnosed Preoperatively?
Joint Authors
Rammohan, Ashwin
Cherukuri, Sathya D.
Sathyanesan, Jeswanth
Palaniappan, Ravichandran
Govindan, Manoharan
Source
Gastroenterology Research and Practice
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-10-27
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Xanthogranulomatous cholecystitis (XGC) is often misdiagnosed as gallbladder cancer (GBC).
We aimed to determine the preoperative characteristics that could potentially aid in an accurate diagnosis of XGC masquerading as GBC.
Methods.
An analysis of patients operated upon with a preoperative diagnosis of GBC between January 2008 and December 2012 was conducted to determine the clinical and radiological features which could assist in a preoperative diagnosis of XGC.
Results.
Out of 77 patients who underwent radical cholecystectomy, 16 were reported as XGC on final histopathology (Group A), while 60 were GBC (Group B).
The incidences of abdominal pain, cholelithiasis, choledocholithiasis, and acute cholecystitis were significantly higher in Group A, while anorexia and weight loss were higher in Group B.
On CT, diffuse gallbladder wall thickening, continuous mucosal line enhancement, and submucosal hypoattenuated nodules were significant findings in Group A.
CT findings on retrospect revealed at least one of these findings in 68.7% of the cases.
Conclusion.
Differentiating XGC from GBC is difficult, and a definitive diagnosis still necessitates a histopathological examination.
An accurate preoperative diagnosis requires an integrated review of clinical and characteristic radiological features, the presence of which may help avoid radical resection and avoidable morbidity in selected cases.
American Psychological Association (APA)
Rammohan, Ashwin& Cherukuri, Sathya D.& Sathyanesan, Jeswanth& Palaniappan, Ravichandran& Govindan, Manoharan. 2014. Xanthogranulomatous Cholecystitis Masquerading as Gallbladder Cancer: Can It Be Diagnosed Preoperatively?. Gastroenterology Research and Practice،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1035877
Modern Language Association (MLA)
Rammohan, Ashwin…[et al.]. Xanthogranulomatous Cholecystitis Masquerading as Gallbladder Cancer: Can It Be Diagnosed Preoperatively?. Gastroenterology Research and Practice No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1035877
American Medical Association (AMA)
Rammohan, Ashwin& Cherukuri, Sathya D.& Sathyanesan, Jeswanth& Palaniappan, Ravichandran& Govindan, Manoharan. Xanthogranulomatous Cholecystitis Masquerading as Gallbladder Cancer: Can It Be Diagnosed Preoperatively?. Gastroenterology Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1035877
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035877