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Determinants of Weight Loss prior to Diagnosis in Inflammatory Bowel Disease: A Retrospective Observational Study
Joint Authors
Elsherif, Yasser
Alexakis, Christopher
Mendall, Michael
Source
Gastroenterology Research and Practice
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-23
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Aims.
To identify prevalence, severity, and environmental determinants of weight loss in inflammatory bowel disease (IBD) patients just prior to time of formal diagnosis.
Methodology.
IBD patients attending outpatient clinic were questioned about weight loss prior to diagnosis and other environmental and demographic variables.
The percentage BMI loss was calculated for each subject and factors associated with weight loss were determined.
Results.
Four hundred and ninety-four subjects were recruited (237 cases of Crohn’s disease (CD) and 257 cases of ulcerative colitis (UC)).
Overall, 57% of subjects with CD and 51% of subjects with UC experienced significant weight loss prior to diagnosis (>5% BMI loss).
Younger age at diagnosis and history of previous IBD surgery were significantly associated with both lower BMI at diagnosis and increased weight loss prior to diagnosis.
In CD patients, increasing age at diagnosis was inversely associated with weight loss prior to diagnosis.
Ileal disease was a risk factor of weight loss, whereas prior appendectomy was associated with reduced risk of weight loss.
Conclusions.
Weight loss is a significant problem for many IBD patients at presentation, especially in younger age and CD with ileal involvement.
Appendectomy is associated with diminished weight loss.
American Psychological Association (APA)
Elsherif, Yasser& Alexakis, Christopher& Mendall, Michael. 2014. Determinants of Weight Loss prior to Diagnosis in Inflammatory Bowel Disease: A Retrospective Observational Study. Gastroenterology Research and Practice،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1035898
Modern Language Association (MLA)
Elsherif, Yasser…[et al.]. Determinants of Weight Loss prior to Diagnosis in Inflammatory Bowel Disease: A Retrospective Observational Study. Gastroenterology Research and Practice No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1035898
American Medical Association (AMA)
Elsherif, Yasser& Alexakis, Christopher& Mendall, Michael. Determinants of Weight Loss prior to Diagnosis in Inflammatory Bowel Disease: A Retrospective Observational Study. Gastroenterology Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1035898
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035898