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Antiviral Treatment among Pregnant Women with Chronic Hepatitis B
Joint Authors
Fan, Lin
Owusu-Edusei, Kwame
Schillie, Sarah F.
Murphy, Trudy V.
Source
Infectious Diseases in Obstetrics and Gynecology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-04
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
To describe the antiviral treatment patterns for chronic hepatitis B (CHB) among pregnant and nonpregnant women.
Methods.
Using 2011 MarketScan claims, we calculated the rates of antiviral treatment among women (aged 10–50 years) with CHB.
We described the pattern of antiviral treatment during pregnancy and ≥1 month after delivery.
Results.
We identified 6274 women with CHB during 2011.
Among these, 64 of 507 (12.6%) pregnant women and 1151 of 5767 (20.0%) nonpregnant women received antiviral treatment (P < 0.01).
Pregnant women were most commonly prescribed tenofovir (73.4%) and lamivudine (21.9%); nonpregnant women were most commonly prescribed tenofovir (50.2%) and entecavir (41.3%) (P < 0.01).
Among 48 treated pregnant women with an identifiable delivery date, 16 (33.3%) were prescribed an antiviral before pregnancy and continued treatment for at least one month after delivery; 14 (29.2%) started treatment during the third trimester and continued at least one month after delivery.
Conclusion.
Among this insured population, pregnant women with CHB received an antiviral significantly less often than nonpregnant women.
The most common antiviral prescribed for pregnant women was tenofovir.
These data provide a baseline for assessing changes in treatment patterns with anticipated increased use of antivirals to prevent breakthrough perinatal hepatitis B virus infection.
American Psychological Association (APA)
Fan, Lin& Owusu-Edusei, Kwame& Schillie, Sarah F.& Murphy, Trudy V.. 2014. Antiviral Treatment among Pregnant Women with Chronic Hepatitis B. Infectious Diseases in Obstetrics and Gynecology،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1035915
Modern Language Association (MLA)
Fan, Lin…[et al.]. Antiviral Treatment among Pregnant Women with Chronic Hepatitis B. Infectious Diseases in Obstetrics and Gynecology No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1035915
American Medical Association (AMA)
Fan, Lin& Owusu-Edusei, Kwame& Schillie, Sarah F.& Murphy, Trudy V.. Antiviral Treatment among Pregnant Women with Chronic Hepatitis B. Infectious Diseases in Obstetrics and Gynecology. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1035915
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035915