The Development and Application of Novel IR and NMR-Based Model for the Evaluation of Carminative Effect of Artemisia judaica L. Essential Oil
Joint Authors
Alzweiri, Muhammed
Alrawashdeh, Ibrahim M.
Bardaweel, Sanaa K.
Source
International Journal of Analytical Chemistry
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-29
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Artemisia judaica L.
is a medicinal plant that is traditionally used to relieve abdominal pains through its carminative activity.
In this study, spectroscopic analysis was employed to investigate the carminative activity associated with A.
judaica.
Using infrared spectroscopy, the carminative activity was evaluated based on the first derivative of IR-characteristic stretching signal of CO2.
Our results indicate that A.
judaica oil effectively reduced the response of CO2 signal equivalent to thymol standard.
Additionally, 1H-NMR spectroscopy was utilized to assess surface activity of A.
judaica crude oil through the reduction of interfacial tension in a D2O/CDCl3 system.
Apparently, 10 mg of the oil was able to solubilize water in a chloroform layer up to 4.3% (w/w).
In order to correlate the observed surface activity of the oil to its actual composition, GC-MS and GC-FID structural analysis were undertaken.
The results revealed that the oil composition consists of oxygenated terpenes which might be responsible for the carminative effect.
Furthermore, owing to its sensitivity, our model provides a fundamental basis for the pharmacological assessment of trace amounts of oils with high precision and accuracy.
American Psychological Association (APA)
Alzweiri, Muhammed& Alrawashdeh, Ibrahim M.& Bardaweel, Sanaa K.. 2014. The Development and Application of Novel IR and NMR-Based Model for the Evaluation of Carminative Effect of Artemisia judaica L. Essential Oil. International Journal of Analytical Chemistry،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1035934
Modern Language Association (MLA)
Alzweiri, Muhammed…[et al.]. The Development and Application of Novel IR and NMR-Based Model for the Evaluation of Carminative Effect of Artemisia judaica L. Essential Oil. International Journal of Analytical Chemistry No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1035934
American Medical Association (AMA)
Alzweiri, Muhammed& Alrawashdeh, Ibrahim M.& Bardaweel, Sanaa K.. The Development and Application of Novel IR and NMR-Based Model for the Evaluation of Carminative Effect of Artemisia judaica L. Essential Oil. International Journal of Analytical Chemistry. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1035934
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035934