Intraoperative Full-Dose of Partial Breast Irradiation with Electrons Delivered by Standard Linear Accelerators for Early Breast Cancer
Joint Authors
Barros, Alfredo Carlos S. D.
Hanna, Samir A.
Carvalho, Heloísa A.
Martella, Eduardo
Andrade, Felipe Eduardo M.
Piato, José Roberto M.
Bevilacqua, José Luiz B.
Source
International Journal of Breast Cancer
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-17
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
To assess feasibility, efficacy, toxicity, and cosmetic results of intraoperative radiotherapy (IORT) with electrons delivered by standard linear accelerators (Linacs) during breast conserving surgeries for early infiltrating breast cancer (BC) treatment.
Materials and Methods.
A total of 152 patients with invasive ductal carcinoma ( T ≤ 3.0 cm) at low risk for local relapses were treated.
All had unicentric lesions by imaging methods and negative sentinel node.
After a wide local excision, 21 Gy were delivered on the parenchyma target volume with electron beams.
Local recurrences (LR), survival, toxicity, and cosmetic outcomes were analyzed.
Results.
The median age was 58.3 years (range 40–85); median follow-up was 50.7 months (range 12–101.5).
There were 5 cases with LR, 2 cases with distant metastases, and 2 cases with deaths related to BC.
The cumulative incidence rates of LR, distant metastases, and BC death were 3.2%, 1.5%, and 1.5%, respectively.
Complications were rare, and the cosmetic results were excellent or good in most of the patients.
Conclusions.
IORT with electrons delivered by standard Linacs is feasible, efficient, and well tolerated and seems to be beneficial for selected patients with early infiltrating BC.
American Psychological Association (APA)
Barros, Alfredo Carlos S. D.& Hanna, Samir A.& Carvalho, Heloísa A.& Martella, Eduardo& Andrade, Felipe Eduardo M.& Piato, José Roberto M.…[et al.]. 2014. Intraoperative Full-Dose of Partial Breast Irradiation with Electrons Delivered by Standard Linear Accelerators for Early Breast Cancer. International Journal of Breast Cancer،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1036305
Modern Language Association (MLA)
Barros, Alfredo Carlos S. D.…[et al.]. Intraoperative Full-Dose of Partial Breast Irradiation with Electrons Delivered by Standard Linear Accelerators for Early Breast Cancer. International Journal of Breast Cancer No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1036305
American Medical Association (AMA)
Barros, Alfredo Carlos S. D.& Hanna, Samir A.& Carvalho, Heloísa A.& Martella, Eduardo& Andrade, Felipe Eduardo M.& Piato, José Roberto M.…[et al.]. Intraoperative Full-Dose of Partial Breast Irradiation with Electrons Delivered by Standard Linear Accelerators for Early Breast Cancer. International Journal of Breast Cancer. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1036305
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1036305