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Antibacterial Efficacy of Iron-Oxide Nanoparticles against Biofilms on Different Biomaterial Surfaces
Joint Authors
Thukkaram, Monica
Sitaram, Soundarya
Kannaiyan, Sathish kumar
Subbiahdoss, Guruprakash
Source
International Journal of Biomaterials
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-23
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Biofilm growth on the implant surface is the number one cause of the failure of the implants.
Biofilms on implant surfaces are hard to eliminate by antibiotics due to the protection offered by the exopolymeric substances that embed the organisms in a matrix, impenetrable for most antibiotics and immune cells.
Application of metals in nanoscale is considered to resolve biofilm formation.
Here we studied the effect of iron-oxide nanoparticles over biofilm formation on different biomaterial surfaces and pluronic coated surfaces.
Bacterial adhesion for 30 min showed significant reduction in bacterial adhesion on pluronic coated surfaces compared to other surfaces.
Subsequently, bacteria were allowed to grow for 24 h in the presence of different concentrations of iron-oxide nanoparticles.
A significant reduction in biofilm growth was observed in the presence of the highest concentration of iron-oxide nanoparticles on pluronic coated surfaces compared to other surfaces.
Therefore, combination of polymer brush coating and iron-oxide nanoparticles could show a significant reduction in biofilm formation.
American Psychological Association (APA)
Thukkaram, Monica& Sitaram, Soundarya& Kannaiyan, Sathish kumar& Subbiahdoss, Guruprakash. 2014. Antibacterial Efficacy of Iron-Oxide Nanoparticles against Biofilms on Different Biomaterial Surfaces. International Journal of Biomaterials،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1036335
Modern Language Association (MLA)
Thukkaram, Monica…[et al.]. Antibacterial Efficacy of Iron-Oxide Nanoparticles against Biofilms on Different Biomaterial Surfaces. International Journal of Biomaterials No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1036335
American Medical Association (AMA)
Thukkaram, Monica& Sitaram, Soundarya& Kannaiyan, Sathish kumar& Subbiahdoss, Guruprakash. Antibacterial Efficacy of Iron-Oxide Nanoparticles against Biofilms on Different Biomaterial Surfaces. International Journal of Biomaterials. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1036335
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1036335