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Body Mass Index and Retinopathy in Type 1 Diabetic Patients
Joint Authors
Novak, Branko
Kaštelan, Helena
Orešković, Darko
Ljubić, Spomenka
Gverović Antunica, Antonela
Salopek Rabatić, Jasminka
Tomić, Martina
Kaštelan, Snježana
Source
International Journal of Endocrinology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-18
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Aim.
To investigate whether body mass index (BMI) independently or in correlation with other risk factors is associated with diabetic retinopathy (DR) progression.
Methods.
The study included 176 patients with type 1 diabetes divided into three groups according to DR status: group 1 (no retinopathy; n = 86 ), group 2 (mild/moderate nonproliferative DR; n = 33 ), and group 3 (severe/very severe NPDR or proliferative DR; n = 57 ).
Results.
A significant deterioration of HbA1c, an increase in total cholesterol, systolic, diastolic blood pressure, and diabetic nephropathy with the progression of retinopathy were found.
DR progression was correlated with diabetes duration, HbA1c, hypertension, total cholesterol, and the presence of nephropathy.
In patients without nephropathy, statistical analyses showed that progression of retinopathy increased significantly with higher BMI (gr.
1: 24.03 ± 3.52, gr.
2: 25.36 ± 3.44, gr.
3: 26.93 ± 3.24; P < 0.01 ).
A positive correlation between BMI and a significant deterioration of HbA1c, an increase in cholesterol, triglycerides, and hypertension was observed.
Conclusion.
BMI in correlation with HbA1c, cholesterol, and hypertension appears to be associated with the progression of DR in type 1 diabetic patients without nephropathy.
However, additional studies are required to investigate the pathogenic role of obesity and weight loss in retinal diabetic complications particularly relating to nephropathy.
American Psychological Association (APA)
Kaštelan, Snježana& Salopek Rabatić, Jasminka& Tomić, Martina& Gverović Antunica, Antonela& Ljubić, Spomenka& Kaštelan, Helena…[et al.]. 2014. Body Mass Index and Retinopathy in Type 1 Diabetic Patients. International Journal of Endocrinology،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1036485
Modern Language Association (MLA)
Kaštelan, Snježana…[et al.]. Body Mass Index and Retinopathy in Type 1 Diabetic Patients. International Journal of Endocrinology No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1036485
American Medical Association (AMA)
Kaštelan, Snježana& Salopek Rabatić, Jasminka& Tomić, Martina& Gverović Antunica, Antonela& Ljubić, Spomenka& Kaštelan, Helena…[et al.]. Body Mass Index and Retinopathy in Type 1 Diabetic Patients. International Journal of Endocrinology. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1036485
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1036485