Determinants of Vitamin D Levels in Italian Children and Adolescents: A Longitudinal Evaluation of Cholecalciferol Supplementation versus the Improvement of Factors Influencing 25(OH)D Status
Joint Authors
Stagi, Stefano
Pelosi, Paola
Strano, Massimo
Poggi, Giovanni
Manoni, Cristina
de Martino, Maurizio
Seminara, Salvatore
Source
International Journal of Endocrinology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-11
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Objective.
This paper aims to assess 25(OH)D levels in Italian children and adolescents identifying risk factors for 25(OH)D deficiency and to evaluate whether a normal 25(OH)D value can be restored in 25(OH)D-deficient patients.
Methods.
We evaluated 25(OH)D levels in 679 Italian children and adolescents (≤10, 11–20, 21–30, and >30 ng/mL were defined as severe deficiency, deficiency, insufficiency, and sufficiency, resp.).
Of these, 365 25(OH)D-deficient were followed up for 1 year; 205 were treated with cholecalciferol (Arm A: 400 I.U.) and 160 by improving the environmental variables influencing 25(OH)D levels (Arm B).
Results.
At cross-sectional evaluation, 11.3% showed sufficiency, 30.0% insufficiency, and 58.7% 25(OH)D deficiency.
Mean 25(OH)D was 19.08 ± 8.44 ng/mL.
At the enrollment time ( T 0 ), no difference was found between Arms A and B with respect to distribution and 25(OH)D levels.
At end time ( T 1 ) 26.0% (29.7% in Arm A versus 20.6% in Arm B) showed sufficiency, 38.4% (42.0% versus 34.4%) insufficiency, and 35.6% (28.3% versus 45.0%) 25(OH)D deficiency.
Mean 25(OH)D level was 23.71 ± 6.83 ng/mL.
Conclusions.
Neither changes of lifestyle nor 400 I.U.
cholecalciferol supplementation alone appears to be sufficient to restore adequate 25(OH)D levels.
American Psychological Association (APA)
Stagi, Stefano& Pelosi, Paola& Strano, Massimo& Poggi, Giovanni& Manoni, Cristina& de Martino, Maurizio…[et al.]. 2014. Determinants of Vitamin D Levels in Italian Children and Adolescents: A Longitudinal Evaluation of Cholecalciferol Supplementation versus the Improvement of Factors Influencing 25(OH)D Status. International Journal of Endocrinology،Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-1036526
Modern Language Association (MLA)
Stagi, Stefano…[et al.]. Determinants of Vitamin D Levels in Italian Children and Adolescents: A Longitudinal Evaluation of Cholecalciferol Supplementation versus the Improvement of Factors Influencing 25(OH)D Status. International Journal of Endocrinology No. 2014 (2014), pp.1-13.
https://search.emarefa.net/detail/BIM-1036526
American Medical Association (AMA)
Stagi, Stefano& Pelosi, Paola& Strano, Massimo& Poggi, Giovanni& Manoni, Cristina& de Martino, Maurizio…[et al.]. Determinants of Vitamin D Levels in Italian Children and Adolescents: A Longitudinal Evaluation of Cholecalciferol Supplementation versus the Improvement of Factors Influencing 25(OH)D Status. International Journal of Endocrinology. 2014. Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-1036526
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1036526