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Risk Factors for Anaplastic Thyroid Cancer
Joint Authors
Zivaljevic, Vladan
Paunovic, Ivan
Diklic, Aleksandar
Sipetic, Sandra
Slijepcevic, N.
Marinkovic, J.
Zivic, R.
Vekic, B.
Kalezic, Nevena
Source
International Journal of Endocrinology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Anaplastic thyroid cancer (ATC) is a form of thyroid cancer with very poor prognosis, but is fortunately quite rare.
Its aetiology is unknown and not well researched.
Aim.
The aim of this study was to identify potential risk factors for ATC.
Material and Method.
Case-control study of 126 ATC patients (77 females and 49 males) and 252 controls individually matched by gender, age, and place of abode.
In statistical analysis we used a Cox regression model.
Results.
Univariate logistic regression showed that the risk factors for ATC are low education level, type B blood group, goitre, other nonthyroid malignancies, diabetes, late menarche, and an early first pregnancy.
Multivariate logistic regression analysis showed that independent risk factors for ATC are low education level (OR = 1.42, 95% CI = 1.09–1.86), type B blood group (OR = 2.41, 95% CI = 1.03–5.66), and goitre (OR = 25–33, 95% CI = 5.66–126.65).
Conclusion.
Independent risk factors for ATC are: low education level, type B blood group, and goitre.
American Psychological Association (APA)
Zivaljevic, Vladan& Slijepcevic, N.& Paunovic, Ivan& Diklic, Aleksandar& Kalezic, Nevena& Marinkovic, J.…[et al.]. 2014. Risk Factors for Anaplastic Thyroid Cancer. International Journal of Endocrinology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1036596
Modern Language Association (MLA)
Zivaljevic, Vladan…[et al.]. Risk Factors for Anaplastic Thyroid Cancer. International Journal of Endocrinology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1036596
American Medical Association (AMA)
Zivaljevic, Vladan& Slijepcevic, N.& Paunovic, Ivan& Diklic, Aleksandar& Kalezic, Nevena& Marinkovic, J.…[et al.]. Risk Factors for Anaplastic Thyroid Cancer. International Journal of Endocrinology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1036596
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1036596